Tharakan R - Search Results

1

Methotrexate-based PROTACs as DHFR-specific chemical probes.

Rana S, Dranchak P, Dahlin JL, Lamy L, Li W, Oliphant E, Shrimp JH, Rajacharya GH, Tharakan R, Holland DO, Whitten AS, Wilson KM, Singh PK, Durum SK, Tao D, Rai G, Inglese J. Rana S, et al. Among authors: tharakan r. Cell Chem Biol. 2024 Feb 15;31(2):221-233.e14. doi: 10.1016/j.chembiol.2023.09.014. Epub 2023 Oct 23. Cell Chem Biol. 2024. PMID: 37875111 Free article.

2

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

Tharakan R, Ubaida-Mohien C, Dunn C, Kaileh M, Tryggvadottir R, Zukley L, Chia CW, Sen R, Ferrucci L. Tharakan R, et al. Aging Cell. 2023 Jul;22(7):e13847. doi: 10.1111/acel.13847. Epub 2023 Jun 12. Aging Cell. 2023. PMID: 37309088 Free PMC article.

3

Understanding the Human Aging Proteome Using Epidemiological Models.

Ubaida-Mohien C, Moaddel R, Moore Z, Kuo PL, Tharakan R, Tanaka T, Ferrucci L. Ubaida-Mohien C, et al. Among authors: tharakan r. Methods Mol Biol. 2022;2399:173-192. doi: 10.1007/978-1-0716-1831-8_8. Methods Mol Biol. 2022. PMID: 35604557

4

Isolated hepatosplenic tuberculosis: a rare presentation with persistent fever in a 2-year-old female child.

Tharakan R, John S, Devdas JM, Hegde P. Tharakan R, et al. BMJ Case Rep. 2021 Aug 13;14(8):e243851. doi: 10.1136/bcr-2021-243851. BMJ Case Rep. 2021. PMID: 34389594 Free PMC article.

5

Proteomics and Epidemiological Models of Human Aging.

Ubaida-Mohien C, Moaddel R, Moore AZ, Kuo PL, Faghri F, Tharakan R, Tanaka T, Nalls MA, Ferrucci L. Ubaida-Mohien C, et al. Among authors: tharakan r. Front Physiol. 2021 May 31;12:674013. doi: 10.3389/fphys.2021.674013. eCollection 2021. Front Physiol. 2021. PMID: 34135771 Free PMC article. Review.

6

Minireview: Novel Micropeptide Discovery by Proteomics and Deep Sequencing Methods.

Tharakan R, Sawa A. Tharakan R, et al. Front Genet. 2021 May 6;12:651485. doi: 10.3389/fgene.2021.651485. eCollection 2021. Front Genet. 2021. PMID: 34025718 Free PMC article. Review.

7

Ribosome profiling analysis of human skeletal muscle identifies reduced translation of mitochondrial proteins with age.

Tharakan R, Ubaida-Mohien C, Piao Y, Gorospe M, Ferrucci L. Tharakan R, et al. RNA Biol. 2021 Nov;18(11):1555-1559. doi: 10.1080/15476286.2021.1875647. Epub 2021 Jan 21. RNA Biol. 2021. PMID: 33472542 Free PMC article.

8

Translational Control during Cellular Senescence.

Payea MJ, Anerillas C, Tharakan R, Gorospe M. Payea MJ, et al. Among authors: tharakan r. Mol Cell Biol. 2021 Jan 25;41(2):e00512-20. doi: 10.1128/MCB.00512-20. Print 2021 Jan 25. Mol Cell Biol. 2021. PMID: 33077499 Free PMC article. Review.

9

Blood DNA Methylation and Aging: A Cross-Sectional Analysis and Longitudinal Validation in the InCHIANTI Study.

Tharakan R, Ubaida-Mohien C, Moore AZ, Hernandez D, Tanaka T, Ferrucci L. Tharakan R, et al. J Gerontol A Biol Sci Med Sci. 2020 Oct 15;75(11):2051-2055. doi: 10.1093/gerona/glaa052. J Gerontol A Biol Sci Med Sci. 2020. PMID: 32147700 Free PMC article.

10

Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria.

Ubaida-Mohien C, Lyashkov A, Gonzalez-Freire M, Tharakan R, Shardell M, Moaddel R, Semba RD, Chia CW, Gorospe M, Sen R, Ferrucci L. Ubaida-Mohien C, et al. Among authors: tharakan r. Elife. 2019 Oct 23;8:e49874. doi: 10.7554/eLife.49874. Elife. 2019. PMID: 31642809 Free PMC article.

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