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Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis.
Redox Biol. 2022 Sep;55:102417. doi: 10.1016/j.redox.2022.102417. Epub 2022 Jul 21.
Redox Biol. 2022.
PMID: 35933902
Free PMC article.
Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K, Szabo C, Chao C, Hellmich MR.
Phillips CM, et al.
Cancer Res. 2017 Nov 1;77(21):5741-5754. doi: 10.1158/0008-5472.CAN-16-3480. Epub 2017 Sep 18.
Cancer Res. 2017.
PMID: 28923859
Free PMC article.
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Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept.
Hellmich MR, Chao C, Módis K, Ding Y, Zatarain JR, Thanki K, Maskey M, Druzhyna N, Untereiner AA, Ahmad A, Xue Y, Chen H, Russell WK, Wang J, Zhou J, Szabo C.
Hellmich MR, et al.
Biomolecules. 2021 Jul 21;11(8):1073. doi: 10.3390/biom11081073.
Biomolecules. 2021.
PMID: 34439739
Free PMC article.
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3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics.
Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli SI, Thanki K, Resto VA, Chao C, Hellmich MR, Szabo C, Papapetropoulos A, Módis K.
Abdollahi Govar A, et al.
Br J Pharmacol. 2020 Feb;177(4):866-883. doi: 10.1111/bph.14574. Epub 2019 Mar 4.
Br J Pharmacol. 2020.
PMID: 30644090
Free PMC article.
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Consensus Molecular Subtypes of Colorectal Cancer and their Clinical Implications.
Thanki K, Nicholls ME, Gajjar A, Senagore AJ, Qiu S, Szabo C, Hellmich MR, Chao C.
Thanki K, et al.
Int Biol Biomed J. 2017 Summer;3(3):105-111. Epub 2017 Jun 13.
Int Biol Biomed J. 2017.
PMID: 28825047
Free PMC article.
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