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Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate.
Thambyrajah R, Maqueda M, Neo WH, Imbach K, Guillén Y, Grases D, Fadlullah Z, Gambera S, Matteini F, Wang X, Calero-Nieto FJ, Esteller M, Florian MC, Porta E, Benedito R, Göttgens B, Lacaud G, Espinosa L, Bigas A. Thambyrajah R, et al. Nat Commun. 2024 Feb 21;15(1):1604. doi: 10.1038/s41467-024-45716-y. Nat Commun. 2024. PMID: 38383534 Free PMC article.
The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation.
Vizán P, Gutiérrez A, Espejo I, García-Montolio M, Lange M, Carretero A, Lafzi A, de Andrés-Aguayo L, Blanco E, Thambyrajah R, Graf T, Heyn H, Bigas A, Di Croce L. Vizán P, et al. Among authors: thambyrajah r. Sci Adv. 2020 Aug 5;6(32):eabb2745. doi: 10.1126/sciadv.abb2745. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32821835 Free PMC article.
Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation.
Porcheri C, Golan O, Calero-Nieto FJ, Thambyrajah R, Ruiz-Herguido C, Wang X, Catto F, Guillén Y, Sinha R, González J, Kinston SJ, Mariani SA, Maglitto A, Vink CS, Dzierzak E, Charbord P, Göttgens B, Espinosa L, Sprinzak D, Bigas A. Porcheri C, et al. Among authors: thambyrajah r. EMBO J. 2020 Apr 15;39(8):e104270. doi: 10.15252/embj.2019104270. Epub 2020 Mar 9. EMBO J. 2020. PMID: 32149421 Free PMC article.
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes.
Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, Roychoudhuri R, Paul F, Klippert J, Hammes A, Willnow T, Göttgens B, Dzierzak E, Zon LI, Lacaud G, Kouskoff V, Pimanda JE. Nasrallah R, et al. Among authors: thambyrajah r. Blood. 2016 Oct 13;128(15):1928-1939. doi: 10.1182/blood-2016-02-697870. Epub 2016 Aug 23. Blood. 2016. PMID: 27554085 Free PMC article.
13 results