Thakur A - Search Results

1

Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship.

Thakur A, Rana M, Ritika, Mathew J, Nepali S, Pan CH, Liou JP, Nepali K. Thakur A, et al. Bioorg Chem. 2023 Dec;141:106893. doi: 10.1016/j.bioorg.2023.106893. Epub 2023 Sep 27. Bioorg Chem. 2023. PMID: 37783100 Review.

2

Steering the antitumor drug discovery campaign towards structurally diverse indolines.

Thakur A, Singh A, Kaur N, Ojha R, Nepali K. Thakur A, et al. Bioorg Chem. 2020 Jan;94:103436. doi: 10.1016/j.bioorg.2019.103436. Epub 2019 Nov 13. Bioorg Chem. 2020. PMID: 31761410 Review.

3

The Role of Epigenetic Mechanisms in Autoimmune, Neurodegenerative, Cardiovascular, and Imprinting Disorders.

Sharma R, Sharma S, Thakur A, Singh A, Singh J, Nepali K, Liou JP. Sharma R, et al. Among authors: thakur a. Mini Rev Med Chem. 2022;22(15):1977-2011. doi: 10.2174/1389557522666220217103441. Mini Rev Med Chem. 2022. PMID: 35176978 Review.

4

Glioblastoma: Current Status, Emerging Targets, and Recent Advances.

Thakur A, Faujdar C, Sharma R, Sharma S, Malik B, Nepali K, Liou JP. Thakur A, et al. J Med Chem. 2022 Jul 14;65(13):8596-8685. doi: 10.1021/acs.jmedchem.1c01946. Epub 2022 Jul 5. J Med Chem. 2022. PMID: 35786935 Free PMC article. Review.

5

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal.

Nepali K, Sharma R, Sharma S, Thakur A, Liou JP. Nepali K, et al. Among authors: thakur a. J Biomed Sci. 2022 Sep 6;29(1):65. doi: 10.1186/s12929-022-00847-6. J Biomed Sci. 2022. PMID: 36064696 Free PMC article. Review.

6

Prudent tactics to sail the boat of PARP inhibitors as therapeutics for diverse malignancies.

Rana M, Thakur A, Kaur C, Pan CH, Lee SB, Liou JP, Nepali K. Rana M, et al. Among authors: thakur a. Expert Opin Drug Discov. 2023 Jul-Dec;18(10):1169-1193. doi: 10.1080/17460441.2023.2241818. Epub 2023 Jul 31. Expert Opin Drug Discov. 2023. PMID: 37525475 Review.

7

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.

Sharma S, Chandra K, Naik A, Sharma A, Sharma R, Thakur A, Grewal AS, Dhingra AK, Banerjee A, Liou JP, Guru SK, Nepali K. Sharma S, et al. Among authors: thakur a. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2276665. doi: 10.1080/14756366.2023.2276665. Epub 2023 Nov 2. J Enzyme Inhib Med Chem. 2023. PMID: 37919954 Free PMC article.

8

N-Heterocycle based Degraders (PROTACs) Manifesting Anticancer Efficacy: Recent Advances.

Banerjee S, Sharma S, Thakur A, Sachdeva R, Sharma R, Nepali K, Liou JP. Banerjee S, et al. Among authors: thakur a. Curr Drug Targets. 2023;24(15):1184-1208. doi: 10.2174/0113894501273969231102095615. Curr Drug Targets. 2023. PMID: 37946353 Review.

9

Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.

Thakur A, Rana M, Mishra A, Kaur C, Pan CH, Nepali K. Thakur A, et al. Eur J Med Chem. 2024 May 6;272:116472. doi: 10.1016/j.ejmech.2024.116472. Online ahead of print. Eur J Med Chem. 2024. PMID: 38728867 Review.

10

Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer's Disease.

Kumar B, Thakur A, Dwivedi AR, Kumar R, Kumar V. Kumar B, et al. Among authors: thakur a. Curr Med Chem. 2022;29(10):1757-1803. doi: 10.2174/0929867328666210512005508. Curr Med Chem. 2022. PMID: 33982650 Review.

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