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Page 1
Computationally restoring the potency of a clinical antibody against Omicron.
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW; Tri-lab COVID-19 Consortium; Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe JE Jr, Carnahan RH, Faissol DM. Desautels TA, et al. Among authors: thackray lb. Nature. 2024 May 8. doi: 10.1038/s41586-024-07385-1. Online ahead of print. Nature. 2024. PMID: 38720086
A compendium of multi-omics data illuminating host responses to lethal human virus infections.
Eisfeld AJ, Anderson LN, Fan S, Walters KB, Halfmann PJ, Westhoff Smith D, Thackray LB, Tan Q, Sims AC, Menachery VD, Schäfer A, Sheahan TP, Cockrell AS, Stratton KG, Webb-Robertson BM, Kyle JE, Burnum-Johnson KE, Kim YM, Nicora CD, Peralta Z, N'jai AU, Sahr F, van Bakel H, Diamond MS, Baric RS, Metz TO, Smith RD, Kawaoka Y, Waters KM. Eisfeld AJ, et al. Among authors: thackray lb. Sci Data. 2024 Apr 2;11(1):328. doi: 10.1038/s41597-024-03124-3. Sci Data. 2024. PMID: 38565538 Free PMC article.
Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans.
Schäfer A, Gralinski LE, Leist SR, Hampton BK, Mooney MA, Jensen KL, Graham RL, Agnihothram S, Jeng S, Chamberlin S, Bell TA, Scobey DT, Linnertz CL, VanBlargan LA, Thackray LB, Hock P, Miller DR, Shaw GD, Diamond MS, de Villena FPM, McWeeney SK, Heise MT, Menachery VD, Ferris MT, Baric RS. Schäfer A, et al. Among authors: thackray lb. Virus Res. 2024 Jun;344:199357. doi: 10.1016/j.virusres.2024.199357. Epub 2024 Mar 23. Virus Res. 2024. PMID: 38508400 Free PMC article.
Domain-based mRNA vaccines encoding spike protein N-terminal and receptor binding domains confer protection against SARS-CoV-2.
Stewart-Jones GBE, Elbashir SM, Wu K, Lee D, Renzi I, Ying B, Koch M, Sein CE, Choi A, Whitener B, Garcia-Dominguez D, Henry C, Woods A, Ma L, Montes Berrueta D, Avena LE, Quinones J, Falcone S, Hsiao CJ, Scheaffer SM, Thackray LB, White P, Diamond MS, Edwards DK, Carfi A. Stewart-Jones GBE, et al. Among authors: thackray lb. Sci Transl Med. 2023 Sep 13;15(713):eadf4100. doi: 10.1126/scitranslmed.adf4100. Epub 2023 Sep 13. Sci Transl Med. 2023. PMID: 37703353
An Antiviral Role for TRIM14 in Ebola Virus Infection.
Kuroda M, Halfmann PJ, Thackray LB, Diamond MS, Feldmann H, Marzi A, Kawaoka Y. Kuroda M, et al. Among authors: thackray lb. J Infect Dis. 2023 Nov 15;228(Suppl 7):S514-S521. doi: 10.1093/infdis/jiad325. J Infect Dis. 2023. PMID: 37562033
Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants.
Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Lillo AM, Sundaram S, Bloom J, Diamond MS, Crowe JE Jr, Carnahan RH, Faissol DM. Desautels TA, et al. Among authors: thackray lb. bioRxiv [Preprint]. 2023 Apr 24:2022.10.21.513237. doi: 10.1101/2022.10.21.513237. bioRxiv. 2023. PMID: 36324800 Free PMC article. Preprint.
Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice.
Scheaffer SM, Lee D, Whitener B, Ying B, Wu K, Liang CY, Jani H, Martin P, Amato NJ, Avena LE, Berrueta DM, Schmidt SD, O'Dell S, Nasir A, Chuang GY, Stewart-Jones G, Koup RA, Doria-Rose NA, Carfi A, Elbashir SM, Thackray LB, Edwards DK, Diamond MS. Scheaffer SM, et al. Among authors: thackray lb. Nat Med. 2023 Jan;29(1):247-257. doi: 10.1038/s41591-022-02092-8. Epub 2022 Oct 20. Nat Med. 2023. PMID: 36265510
Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant.
Scheaffer SM, Lee D, Whitener B, Ying B, Wu K, Jani H, Martin P, Amato NJ, Avena LE, Berrueta DM, Schmidt SD, O'Dell S, Nasir A, Chuang GY, Stewart-Jones G, Koup RA, Doria-Rose NA, Carfi A, Elbashir SM, Thackray LB, Edwards DK, Diamond MS. Scheaffer SM, et al. Among authors: thackray lb. bioRxiv [Preprint]. 2022 Sep 13:2022.09.12.507614. doi: 10.1101/2022.09.12.507614. bioRxiv. 2022. PMID: 36263060 Free PMC article. Updated. Preprint.
Development of SARS-CoV-2 mRNA vaccines encoding spike N-terminal and receptor binding domains.
Stewart-Jones GBE, Elbashir SM, Wu K, Lee D, Renzi I, Ying B, Koch M, Sein CE, Choi A, Whitener B, Garcia-Dominguez D, Henry C, Woods A, Ma L, Montes Berrueta D, Avena LE, Quinones J, Falcone S, Hsiao CJ, Scheaffer SM, Thackray LB, White P, Diamond MS, Edwards DK, Carfi A. Stewart-Jones GBE, et al. Among authors: thackray lb. bioRxiv [Preprint]. 2022 Oct 7:2022.10.07.511319. doi: 10.1101/2022.10.07.511319. bioRxiv. 2022. PMID: 36238717 Free PMC article. Updated. Preprint.
67 results