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Page 1
FACS-assisted CRISPR-Cas9 genome editing of human induced pluripotent stem cells.
Caillaud A, Lévêque A, Thédrez A, Girardeau A, Canac R, Bray L, Baudic M, Barc J, Gaborit N, Lamirault G, Gardie B, Idriss S, Rimbert A, Le May C, Cariou B, Si-Tayeb K. Caillaud A, et al. Among authors: thedrez a. STAR Protoc. 2022 Dec 16;3(4):101680. doi: 10.1016/j.xpro.2022.101680. Epub 2022 Sep 16. STAR Protoc. 2022. PMID: 36115027 Free PMC article.
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia.
Dijk W, Di Filippo M, Kooijman S, van Eenige R, Rimbert A, Caillaud A, Thedrez A, Arnaud L, Pronk A, Garçon D, Sotin T, Lindenbaum P, Ozcariz Garcia E, Pais de Barros JP, Duvillard L, Si-Tayeb K, Amigo N, Le Questel JY, Rensen PCN, Le May C, Moulin P, Cariou B. Dijk W, et al. Among authors: thedrez a. Circulation. 2022 Sep 6;146(10):724-739. doi: 10.1161/CIRCULATIONAHA.121.057978. Epub 2022 Jul 28. Circulation. 2022. PMID: 35899625 Free PMC article.
Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes.
Ramin-Mangata S, Wargny M, Pichelin M, Le May C, Thédrez A, Blanchard V, Nativel B, Santos RD, Benseñor IM, Lotufo PA, Lambert G, Cariou B. Ramin-Mangata S, et al. Among authors: thedrez a. Atherosclerosis. 2020 Jan;293:49-56. doi: 10.1016/j.atherosclerosis.2019.11.027. Epub 2019 Nov 28. Atherosclerosis. 2020. PMID: 31835041
Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function.
Ramin-Mangata S, Thedrez A, Nativel B, Diotel N, Blanchard V, Wargny M, Aguesse A, Billon-Crossouard S, Vindis C, Le May C, Hulin P, Armanet M, Gmyr V, Pattou F, Croyal M, Meilhac O, Nobécourt E, Cariou B, Lambert G. Ramin-Mangata S, et al. Among authors: thedrez a. Atherosclerosis. 2021 Jun;326:47-55. doi: 10.1016/j.atherosclerosis.2021.03.044. Epub 2021 Apr 20. Atherosclerosis. 2021. PMID: 33933263
PCSK9 is not secreted from mature differentiated intestinal cells.
Moreau F, Thédrez A, Garçon D, Ayer A, Sotin T, Dijk W, Blanchard C, Chadeuf G, Arnaud L, Croyal M, Van Landeghem L, Touvron M, Prieur X, Roubtsova A, Seidah N, Prat A, Cariou B, Le May C. Moreau F, et al. Among authors: thedrez a. J Lipid Res. 2021;62:100096. doi: 10.1016/j.jlr.2021.100096. Epub 2021 Jul 17. J Lipid Res. 2021. PMID: 34280453 Free PMC article.
Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab.
Thedrez A, Blom DJ, Ramin-Mangata S, Blanchard V, Croyal M, Chemello K, Nativel B, Pichelin M, Cariou B, Bourane S, Tang L, Farnier M, Raal FJ, Lambert G. Thedrez A, et al. Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):592-598. doi: 10.1161/ATVBAHA.117.310217. Epub 2017 Dec 28. Arterioscler Thromb Vasc Biol. 2018. PMID: 29284604 Free PMC article. Clinical Trial.
Corrigendum: PCSK9 is not secreted from mature differentiated intestinal cells.
Moreau F, Thédrez A, Garçon D, Ayer A, Sotin T, Dijk W, Blanchard C, Chadeuf G, Arnaud L, Croyal M, Van Landeghem L, Touvron M, Prieur X, Roubtsova A, Seidah N, Prat A, Cariou B, Le May C. Moreau F, et al. Among authors: thedrez a. J Lipid Res. 2022 Apr;63(4):100186. doi: 10.1016/j.jlr.2022.100186. Epub 2022 Mar 14. J Lipid Res. 2022. PMID: 35298954 Free PMC article. No abstract available.
Proprotein Convertase Subtilisin Kexin Type 9 Inhibition for Autosomal Recessive Hypercholesterolemia-Brief Report.
Thedrez A, Sjouke B, Passard M, Prampart-Fauvet S, Guédon A, Croyal M, Dallinga-Thie G, Peter J, Blom D, Ciccarese M, Cefalù AB, Pisciotta L, Santos RD, Averna M, Raal F, Pintus P, Cossu M, Hovingh K, Lambert G. Thedrez A, et al. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1647-50. doi: 10.1161/ATVBAHA.116.307493. Epub 2016 Apr 14. Arterioscler Thromb Vasc Biol. 2016. PMID: 27079874
PCSK9 inhibition with alirocumab reduces lipoprotein(a) levels in nonhuman primates by lowering apolipoprotein(a) production rate.
Croyal M, Tran TT, Blanchard RH, Le Bail JC, Villard EF, Poirier B, Aguesse A, Billon-Crossouard S, Ramin-Mangata S, Blanchard V, Nativel B, Chemello K, Khantalin I, Thedrez A, Janiak P, Krempf M, Boixel C, Lambert G, Guillot E. Croyal M, et al. Among authors: thedrez a. Clin Sci (Lond). 2018 May 31;132(10):1075-1083. doi: 10.1042/CS20180040. Print 2018 May 31. Clin Sci (Lond). 2018. PMID: 29724769
PCSK9 and lipoprotein (a) levels are two predictors of coronary artery calcification in asymptomatic patients with familial hypercholesterolemia.
Alonso R, Mata P, Muñiz O, Fuentes-Jimenez F, Díaz JL, Zambón D, Tomás M, Martin C, Moyon T, Croyal M, Thedrez A, Lambert G. Alonso R, et al. Among authors: thedrez a. Atherosclerosis. 2016 Nov;254:249-253. doi: 10.1016/j.atherosclerosis.2016.08.038. Epub 2016 Aug 27. Atherosclerosis. 2016. PMID: 27594539
24 results