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Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach.
Wright MH, Clough B, Rackham MD, Rangachari K, Brannigan JA, Grainger M, Moss DK, Bottrill AR, Heal WP, Broncel M, Serwa RA, Brady D, Mann DJ, Leatherbarrow RJ, Tewari R, Wilkinson AJ, Holder AA, Tate EW. Wright MH, et al. Among authors: tewari r. Nat Chem. 2014 Feb;6(2):112-21. doi: 10.1038/nchem.1830. Epub 2013 Dec 22. Nat Chem. 2014. PMID: 24451586 Free PMC article.
Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation.
Guttery DS, Poulin B, Ramaprasad A, Wall RJ, Ferguson DJ, Brady D, Patzewitz EM, Whipple S, Straschil U, Wright MH, Mohamed AM, Radhakrishnan A, Arold ST, Tate EW, Holder AA, Wickstead B, Pain A, Tewari R. Guttery DS, et al. Among authors: tewari r. Cell Host Microbe. 2014 Jul 9;16(1):128-40. doi: 10.1016/j.chom.2014.05.020. Cell Host Microbe. 2014. PMID: 25011111 Free PMC article.
Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility.
Green JL, Wall RJ, Vahokoski J, Yusuf NA, Ridzuan MAM, Stanway RR, Stock J, Knuepfer E, Brady D, Martin SR, Howell SA, Pires IP, Moon RW, Molloy JE, Kursula I, Tewari R, Holder AA. Green JL, et al. Among authors: tewari r. J Biol Chem. 2017 Oct 27;292(43):17857-17875. doi: 10.1074/jbc.M117.802769. Epub 2017 Sep 11. J Biol Chem. 2017. PMID: 28893907 Free PMC article.
429 results