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KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes.
Barbagiovanni G, Germain PL, Zech M, Atashpaz S, Lo Riso P, D'Antonio-Chronowska A, Tenderini E, Caiazzo M, Boesch S, Jech R, Haslinger B, Broccoli V, Stewart AF, Winkelmann J, Testa G. Barbagiovanni G, et al. Among authors: testa g. Cell Rep. 2018 Oct 23;25(4):988-1001. doi: 10.1016/j.celrep.2018.09.067. Cell Rep. 2018. PMID: 30355503 Free PMC article.
Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis.
López-Tobón A, Villa CE, Cheroni C, Trattaro S, Caporale N, Conforti P, Iennaco R, Lachgar M, Rigoli MT, Marcó de la Cruz B, Lo Riso P, Tenderini E, Troglio F, De Simone M, Liste-Noya I, Macino G, Pagani M, Cattaneo E, Testa G. López-Tobón A, et al. Among authors: testa g. Stem Cell Reports. 2019 Nov 12;13(5):847-861. doi: 10.1016/j.stemcr.2019.09.005. Epub 2019 Oct 10. Stem Cell Reports. 2019. PMID: 31607568 Free PMC article.
A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high-grade serous ovarian cancer.
Lo Riso P, Villa CE, Gasparoni G, Vingiani A, Luongo R, Manfredi A, Jungmann A, Bertolotti A, Borgo F, Garbi A, Lupia M, Laise P, Das V, Pruneri G, Viale G, Colombo N, Manzo T, Nezi L, Cavallaro U, Cacchiarelli D, Walter J, Testa G. Lo Riso P, et al. Among authors: testa g. Genome Med. 2020 Oct 30;12(1):94. doi: 10.1186/s13073-020-00786-7. Genome Med. 2020. PMID: 33121525 Free PMC article.
Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancer.
Velletri T, Villa CE, Cilli D, Barzaghi B, Lo Riso P, Lupia M, Luongo R, López-Tobón A, De Simone M, Bonnal RJP, Marelli L, Piccolo S, Colombo N, Pagani M, Cavallaro U, Minucci S, Testa G. Velletri T, et al. Among authors: testa g. Cell Death Differ. 2022 Mar;29(3):614-626. doi: 10.1038/s41418-021-00878-w. Epub 2021 Nov 29. Cell Death Differ. 2022. PMID: 34845371 Free PMC article.
Integrated molecular profiling of patient-derived ovarian cancer models identifies clinically relevant signatures and tumor vulnerabilities.
Lupia M, Melocchi V, Bizzaro F, Lo Riso P, Dama E, Baronio M, Ranghiero A, Barberis M, Bernard L, Bertalot G, Giavazzi R, Testa G, Bianchi F, Cavallaro U. Lupia M, et al. Among authors: testa g. Int J Cancer. 2022 Jul 15;151(2):240-254. doi: 10.1002/ijc.33983. Epub 2022 Mar 14. Int J Cancer. 2022. PMID: 35218560 Free PMC article.
Cell reprogramming requires silencing of a core subset of polycomb targets.
Fragola G, Germain PL, Laise P, Cuomo A, Blasimme A, Gross F, Signaroldi E, Bucci G, Sommer C, Pruneri G, Mazzarol G, Bonaldi T, Mostoslavsky G, Casola S, Testa G. Fragola G, et al. Among authors: testa g. PLoS Genet. 2013;9(2):e1003292. doi: 10.1371/journal.pgen.1003292. Epub 2013 Feb 28. PLoS Genet. 2013. PMID: 23468641 Free PMC article.
7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages.
Adamo A, Atashpaz S, Germain PL, Zanella M, D'Agostino G, Albertin V, Chenoweth J, Micale L, Fusco C, Unger C, Augello B, Palumbo O, Hamilton B, Carella M, Donti E, Pruneri G, Selicorni A, Biamino E, Prontera P, McKay R, Merla G, Testa G. Adamo A, et al. Among authors: testa g. Nat Genet. 2015 Feb;47(2):132-41. doi: 10.1038/ng.3169. Epub 2014 Dec 15. Nat Genet. 2015. PMID: 25501393
977 results