Testa A - Search Results

1

PET Tracers To Study Clinically Relevant Hepatic Transporters.

Testa A, Zanda M, Elmore CS, Sharma P. Testa A, et al. Mol Pharm. 2015 Jul 6;12(7):2203-16. doi: 10.1021/acs.molpharmaceut.5b00059. Epub 2015 Jun 16. Mol Pharm. 2015. PMID: 26034841 Review.

2

Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters.

Testa A, Dall'Angelo S, Mingarelli M, Augello A, Schweiger L, Welch A, Elmore CS, Sharma P, Zanda M. Testa A, et al. Bioorg Med Chem. 2017 Feb 1;25(3):963-976. doi: 10.1016/j.bmc.2016.12.008. Epub 2016 Dec 9. Bioorg Med Chem. 2017. PMID: 28011201

3

Preclinical Evaluation of [¹⁸F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters.

Testa A, Dall'Angelo S, Mingarelli M, Augello A, Schweiger L, Welch A, Elmore CS, Dawson D, Sharma P, Zanda M. Testa A, et al. Contrast Media Mol Imaging. 2018 Jul 30;2018:3064751. doi: 10.1155/2018/3064751. eCollection 2018. Contrast Media Mol Imaging. 2018. PMID: 30154685 Free PMC article.

4

High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging α_v β₃ Integrin.

Piras M, Testa A, Fleming IN, Dall'Angelo S, Andriu A, Menta S, Mori M, Brown GD, Forster D, Williams KJ, Zanda M. Piras M, et al. Among authors: testa a. ChemMedChem. 2017 Jul 20;12(14):1142-1151. doi: 10.1002/cmdc.201700328. Epub 2017 Jul 3. ChemMedChem. 2017. PMID: 28608961

5

Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline.

Sani M, Lazzari P, Folini M, Spiga M, Zuco V, De Cesare M, Manca I, Dall'Angelo S, Frigerio M, Usai I, Testa A, Zaffaroni N, Zanda M. Sani M, et al. Among authors: testa a. Chemistry. 2017 Apr 27;23(24):5842-5850. doi: 10.1002/chem.201700874. Epub 2017 Apr 12. Chemistry. 2017. PMID: 28300330

6

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs.

Girardini M, Maniaci C, Hughes SJ, Testa A, Ciulli A. Girardini M, et al. Among authors: testa a. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479. doi: 10.1016/j.bmc.2019.02.048. Epub 2019 Feb 22. Bioorg Med Chem. 2019. PMID: 30826187 Free PMC article.

7

Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds.

Chan KH, Zengerle M, Testa A, Ciulli A. Chan KH, et al. Among authors: testa a. J Med Chem. 2018 Jan 25;61(2):504-513. doi: 10.1021/acs.jmedchem.6b01912. Epub 2017 Jun 22. J Med Chem. 2018. PMID: 28595007 Free PMC article.

8

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7.

Zoppi V, Hughes SJ, Maniaci C, Testa A, Gmaschitz T, Wieshofer C, Koegl M, Riching KM, Daniels DL, Spallarossa A, Ciulli A. Zoppi V, et al. Among authors: testa a. J Med Chem. 2019 Jan 24;62(2):699-726. doi: 10.1021/acs.jmedchem.8b01413. Epub 2018 Dec 28. J Med Chem. 2019. PMID: 30540463 Free PMC article.

9

Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.

Morreale FE, Testa A, Chaugule VK, Bortoluzzi A, Ciulli A, Walden H. Morreale FE, et al. Among authors: testa a. J Med Chem. 2017 Oct 12;60(19):8183-8191. doi: 10.1021/acs.jmedchem.7b01071. Epub 2017 Oct 3. J Med Chem. 2017. PMID: 28933844 Free PMC article.

10

Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins.

Bond AG, Craigon C, Chan KH, Testa A, Karapetsas A, Fasimoye R, Macartney T, Blow JJ, Alessi DR, Ciulli A. Bond AG, et al. Among authors: testa a. J Med Chem. 2021 Oct 28;64(20):15477-15502. doi: 10.1021/acs.jmedchem.1c01532. Epub 2021 Oct 15. J Med Chem. 2021. PMID: 34652918 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

1,052 results

Search Page