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Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents.
Rui M, Rossi D, Marra A, Paolillo M, Schinelli S, Curti D, Tesei A, Cortesi M, Zamagni A, Laurini E, Pricl S, Schepmann D, Wűnsch B, Urban E, Pace V, Collina S. Rui M, et al. Among authors: tesei a. Eur J Med Chem. 2016 Nov 29;124:649-665. doi: 10.1016/j.ejmech.2016.08.067. Epub 2016 Aug 31. Eur J Med Chem. 2016. PMID: 27614411
1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment.
Ferroni C, Pepe A, Kim YS, Lee S, Guerrini A, Parenti MD, Tesei A, Zamagni A, Cortesi M, Zaffaroni N, De Cesare M, Beretta GL, Trepel JB, Malhotra SV, Varchi G. Ferroni C, et al. Among authors: tesei a. J Med Chem. 2017 Apr 13;60(7):3082-3093. doi: 10.1021/acs.jmedchem.7b00105. Epub 2017 Mar 20. J Med Chem. 2017. PMID: 28272894 Free PMC article.
Anticancer drug discovery using multicellular tumor spheroid models.
Zanoni M, Pignatta S, Arienti C, Bonafè M, Tesei A. Zanoni M, et al. Among authors: tesei a. Expert Opin Drug Discov. 2019 Mar;14(3):289-301. doi: 10.1080/17460441.2019.1570129. Epub 2019 Jan 28. Expert Opin Drug Discov. 2019. PMID: 30689452 Review.
Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.
Tesei A, Cortesi M, Pignatta S, Arienti C, Dondio GM, Bigogno C, Malacrida A, Miloso M, Meregalli C, Chiorazzi A, Carozzi V, Cavaletti G, Rui M, Marra A, Rossi D, Collina S. Tesei A, et al. Front Pharmacol. 2019 May 14;10:490. doi: 10.3389/fphar.2019.00490. eCollection 2019. Front Pharmacol. 2019. PMID: 31156430 Free PMC article.
130 results