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Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors.
Di Micco S, Terracciano S, Pierri M, Cantone V, Liening S, König S, Garscha U, Hofstetter RK, Koeberle A, Werz O, Bruno I, Bifulco G. Di Micco S, et al. Among authors: terracciano s. ChemMedChem. 2022 Nov 18;17(22):e202200327. doi: 10.1002/cmdc.202200327. Epub 2022 Oct 11. ChemMedChem. 2022. PMID: 36111583 Free PMC article.
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme.
Lauro G, Tortorella P, Bertamino A, Ostacolo C, Koeberle A, Fischer K, Bruno I, Terracciano S, Gomez-Monterrey IM, Tauro M, Loiodice F, Novellino E, Riccio R, Werz O, Campiglia P, Bifulco G. Lauro G, et al. Among authors: terracciano s. ChemMedChem. 2016 Mar 17;11(6):612-9. doi: 10.1002/cmdc.201500598. Epub 2016 Feb 24. ChemMedChem. 2016. PMID: 26915684
Discovery of new potent molecular entities able to inhibit mPGES-1.
Di Micco S, Terracciano S, Cantone V, Fischer K, Koeberle A, Foglia A, Riccio R, Werz O, Bruno I, Bifulco G. Di Micco S, et al. Among authors: terracciano s. Eur J Med Chem. 2018 Jan 1;143:1419-1427. doi: 10.1016/j.ejmech.2017.10.039. Epub 2017 Oct 23. Eur J Med Chem. 2018. PMID: 29133047
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2 Levels.
Chini MG, Giordano A, Potenza M, Terracciano S, Fischer K, Vaccaro MC, Colarusso E, Bruno I, Riccio R, Koeberle A, Werz O, Bifulco G. Chini MG, et al. Among authors: terracciano s. ACS Med Chem Lett. 2020 Mar 5;11(5):783-789. doi: 10.1021/acsmedchemlett.9b00618. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435385 Free PMC article.
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening.
Lauro G, Manfra M, Pedatella S, Fischer K, Cantone V, Terracciano S, Bertamino A, Ostacolo C, Gomez-Monterrey I, De Nisco M, Riccio R, Novellino E, Werz O, Campiglia P, Bifulco G. Lauro G, et al. Among authors: terracciano s. Eur J Med Chem. 2017 Jan 5;125:278-287. doi: 10.1016/j.ejmech.2016.09.042. Epub 2016 Sep 14. Eur J Med Chem. 2017. PMID: 27688183
86 results