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The unconventional G-protein cycle of LRRK2 and Roco proteins.
Biochem Soc Trans. 2016 Dec 15;44(6):1611-1616. doi: 10.1042/BST20160224.
Biochem Soc Trans. 2016.
PMID: 27913669
Review.
Revisiting the Roco G-protein cycle.
Terheyden S, Ho FY, Gilsbach BK, Wittinghofer A, Kortholt A.
Terheyden S, et al.
Biochem J. 2015 Jan 1;465(1):139-47. doi: 10.1042/BJ20141095.
Biochem J. 2015.
PMID: 25317655
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A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover.
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R, Kortholt A, Versées W.
Deyaert E, et al. Among authors: terheyden s.
Nat Commun. 2017 Oct 18;8(1):1008. doi: 10.1038/s41467-017-01103-4.
Nat Commun. 2017.
PMID: 29044096
Free PMC article.
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Biochemical and kinetic properties of the complex Roco G-protein cycle.
Wauters L, Terheyden S, Gilsbach BK, Leemans M, Athanasopoulos PS, Guaitoli G, Wittinghofer A, Gloeckner CJ, Versées W, Kortholt A.
Wauters L, et al. Among authors: terheyden s.
Biol Chem. 2018 Nov 27;399(12):1447-1456. doi: 10.1515/hsz-2018-0227.
Biol Chem. 2018.
PMID: 30067506
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Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
Lategahn J, Hardick J, Grabe T, Niggenaber J, Jeyakumar K, Keul M, Tumbrink HL, Becker C, Hodson L, Kirschner T, Klövekorn P, Ketzer J, Baumann M, Terheyden S, Unger A, Weisner J, Müller MP, van Otterlo WAL, Bauer S, Rauh D.
Lategahn J, et al. Among authors: terheyden s.
J Med Chem. 2020 Oct 22;63(20):11725-11755. doi: 10.1021/acs.jmedchem.0c00870. Epub 2020 Sep 30.
J Med Chem. 2020.
PMID: 32931277
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Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety.
Scholz O, Huß E, Otter S, Herebian D, Hamacher A, Levy LM, Hristeva S, Sanz M, Ajani H, Puentes AR, Hoffmann T, Hogeback J, Unger A, Terheyden S, Reina do Fundo M, Dewidar B, Roden M, Lammert E.
Scholz O, et al. Among authors: terheyden s.
Mol Metab. 2023 Sep;75:101775. doi: 10.1016/j.molmet.2023.101775. Epub 2023 Jul 12.
Mol Metab. 2023.
PMID: 37451343
Free PMC article.
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Mitochondria-Related Nuclear Gene Expression in the Nucleus Accumbens and Blood Mitochondrial Copy Number After Developmental Fentanyl Exposure in Adolescent Male and Female C57BL/6 Mice.
Calarco CA, Fox ME, Van Terheyden S, Turner MD, Alipio JB, Chandra R, Lobo MK.
Calarco CA, et al. Among authors: van terheyden s.
Front Psychiatry. 2021 Nov 18;12:737389. doi: 10.3389/fpsyt.2021.737389. eCollection 2021.
Front Psychiatry. 2021.
PMID: 34867530
Free PMC article.
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Man with right foot wound.
van Terheyden S, Gingold DB, Tewelde S, Gatz JD.
van Terheyden S, et al.
J Am Coll Emerg Physicians Open. 2021 Aug 18;2(4):e12541. doi: 10.1002/emp2.12541. eCollection 2021 Aug.
J Am Coll Emerg Physicians Open. 2021.
PMID: 34435193
Free PMC article.
No abstract available.
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