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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2005 | 1 |
2007 | 1 |
2008 | 1 |
2015 | 2 |
2019 | 1 |
2024 | 0 |
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6 results
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Page 1
Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells.
Pharmaceuticals (Basel). 2019 Jun 21;12(2):98. doi: 10.3390/ph12020098.
Pharmaceuticals (Basel). 2019.
PMID: 31234364
Free PMC article.
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist.
Monn JA, Prieto L, Taboada L, Hao J, Reinhard MR, Henry SS, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, Marcos A, Blanco J, Bures M, Clawson DK, Atwell S, Lu F, Wang J, Russell M, Heinz BA, Wang X, Carter JH, Getman BG, Catlow JT, Swanson S, Johnson BG, Shaw DB, McKinzie DL.
Monn JA, et al. Among authors: man t.
J Med Chem. 2015 Sep 24;58(18):7526-48. doi: 10.1021/acs.jmedchem.5b01124.
J Med Chem. 2015.
PMID: 26313429
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Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.
Monn JA, Prieto L, Taboada L, Pedregal C, Hao J, Reinhard MR, Henry SS, Goldsmith PJ, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, Marcos A, Blanco J, Bures M, Clawson DK, Atwell S, Lu F, Wang J, Russell M, Heinz BA, Wang X, Carter JH, Xiang C, Catlow JT, Swanson S, Sanger H, Broad LM, Johnson MP, Knopp KL, Simmons RM, Johnson BG, Shaw DB, McKinzie DL.
Monn JA, et al. Among authors: man t.
J Med Chem. 2015 Feb 26;58(4):1776-94. doi: 10.1021/jm501612y. Epub 2015 Feb 5.
J Med Chem. 2015.
PMID: 25602126
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Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
Perry KW, Falcone JF, Fell MJ, Ryder JW, Yu H, Love PL, Katner J, Gordon KD, Wade MR, Man T, Nomikos GG, Phebus LA, Cauvin AJ, Johnson KW, Jones CK, Hoffmann BJ, Sandusky GE, Walter MW, Porter WJ, Yang L, Merchant KM, Shannon HE, Svensson KA.
Perry KW, et al. Among authors: man t.
Neuropharmacology. 2008 Oct;55(5):743-54. doi: 10.1016/j.neuropharm.2008.06.016. Epub 2008 Jun 17.
Neuropharmacology. 2008.
PMID: 18602930
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Discovery and SAR studies of novel GlyT1 inhibitors.
Walter MW, Hoffman BJ, Gordon K, Johnson K, Love P, Jones M, Man T, Phebus L, Reel JK, Rudyk HC, Shannon H, Svensson K, Yu H, Valli MJ, Porter WJ.
Walter MW, et al. Among authors: man t.
Bioorg Med Chem Lett. 2007 Sep 15;17(18):5233-8. doi: 10.1016/j.bmcl.2007.06.074. Epub 2007 Jun 30.
Bioorg Med Chem Lett. 2007.
PMID: 17629697
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Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors.
Boot J, Cases M, Clark BP, Findlay J, Gallagher PT, Hayhurst L, Man T, Montalbetti C, Rathmell RE, Rudyk H, Walter MW, Whatton M, Wood V.
Boot J, et al. Among authors: man t.
Bioorg Med Chem Lett. 2005 Feb 1;15(3):699-703. doi: 10.1016/j.bmcl.2004.11.025.
Bioorg Med Chem Lett. 2005.
PMID: 15664840
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