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Page 1
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, Jiang L, Yin J, Ye L, Su DF, Yang J, Xie G, Keystone E, Westra HJ, Esko T, Metspalu A, Zhou X, Gupta N, Mirel D, Stahl EA, Diogo D, Cui J, Liao K, Guo MH, Myouzen K, Kawaguchi T, Coenen MJ, van Riel PL, van de Laar MA, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Bridges SL Jr, Zhernakova A, Toes RE, Tak PP, Miceli-Richard C, Bang SY, Lee HS, Martin J, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Rantapää-Dahlqvist S, Arlestig L, Choi HK, Kamatani Y, Galan P, Lathrop M; RACI consortium; GARNET consortium; Eyre S, Bowes J, Barton A, de Vries N, Moreland LW, Criswell LA, Karlson EW, Taniguchi A, Yamada R, Kubo M, Liu JS, Bae SC, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Raychaudhuri S, Stranger BE, De Jager PL, Franke L, Visscher PM, Brown MA, Yamanaka H, Mimori T, Takahashi A, Xu H, Behrens TW, Siminovitch KA, Momohara S, Matsuda F, Yamamoto K, Plenge RM. Okada Y, et al. Among authors: terao c. Nature. 2014 Feb 20;506(7488):376-81. doi: 10.1038/nature12873. Epub 2013 Dec 25. Nature. 2014. PMID: 24390342 Free PMC article.
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, Yamazaki K, Hosono N, Myouzen K, Tsunoda T, Kamatani N, Furuichi T, Ikegawa S, Ohmura K, Mimori T, Matsuda F, Iwamoto T, Momohara S, Yamanaka H, Yamada R, Kubo M, Nakamura Y, Yamamoto K. Kochi Y, et al. Among authors: terao c. Nat Genet. 2010 Jun;42(6):515-9. doi: 10.1038/ng.583. Epub 2010 May 9. Nat Genet. 2010. PMID: 20453841
Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis.
Ohmura K, Terao C, Maruya E, Katayama M, Matoba K, Shimada K, Murasawa A, Honjo S, Takasugi K, Tohma S, Matsuo K, Tajima K, Yukawa N, Kawabata D, Nojima T, Fujii T, Yamada R, Saji H, Matsuda F, Mimori T. Ohmura K, et al. Among authors: terao c. Rheumatology (Oxford). 2010 Dec;49(12):2298-304. doi: 10.1093/rheumatology/keq273. Epub 2010 Sep 9. Rheumatology (Oxford). 2010. PMID: 20833643 Free PMC article.
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y; Human Disease Genomics Working Group; RA Clinical and Genetic Study Consortium; Okada Y, Nakamura Y, Yamamoto K, Melchers I, Lathrop M, Mimori T, Matsuda F. Terao C, et al. Hum Mol Genet. 2011 Jul 1;20(13):2680-5. doi: 10.1093/hmg/ddr161. Epub 2011 Apr 19. Hum Mol Genet. 2011. PMID: 21505073
A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations.
Meziani R, Yamada R, Takahashi M, Ohigashi K, Morinobu A, Terao C, Hiratani H, Ohmura K, Yamaguchi M, Nomura T, Vasilescu A, Kokubo M, Renault V, Hirosawa K, Ratanajaraya C, Heath S, Mimori T, Sakaguchi S, Lathrop M, Melchers I, Kumagai S, Matsuda F. Meziani R, et al. Among authors: terao c. Mod Rheumatol. 2012 Feb;22(1):52-8. doi: 10.1007/s10165-011-0467-y. Epub 2011 May 24. Mod Rheumatol. 2012. PMID: 21607711
Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses.
Terao C, Ohmura K, Katayama M, Takahashi M, Kokubo M, Diop G, Toda Y, Yamamoto N; Human Disease Genomics Working Group; Rheumatoid Arthritis (RA) Clinical and Genetic Study Consortium; Shinkura R, Shimizu M, Gut I, Heath S, Melchers I, Manabe T, Lathrop M, Mimori T, Yamada R, Matsuda F. Terao C, et al. PLoS One. 2011;6(6):e20457. doi: 10.1371/journal.pone.0020457. Epub 2011 Jun 3. PLoS One. 2011. PMID: 21673997 Free PMC article.
A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects.
Terao C, Ohmura K, Kochi Y, Ikari K, Maruya E, Katayama M, Shimada K, Murasawa A, Honjo S, Takasugi K, Matsuo K, Tajima K, Suzuki A, Yamamoto K, Momohara S, Yamanaka H, Yamada R, Saji H, Matsuda F, Mimori T. Terao C, et al. Ann Rheum Dis. 2011 Dec;70(12):2134-9. doi: 10.1136/annrheumdis-2011-200353. Epub 2011 Aug 27. Ann Rheum Dis. 2011. PMID: 21873689 Free article.
235 results