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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.
Nelvagal HR, Eaton SL, Wang SH, Eultgen EM, Takahashi K, Le SQ, Nesbitt R, Dearborn JT, Siano N, Puhl AC, Dickson PI, Thompson G, Murdoch F, Brennan PM, Gray M, Greenhalgh SN, Tennant P, Gregson R, Clutton E, Nixon J, Proudfoot C, Guido S, Lillico SG, Whitelaw CBA, Lu JY, Hofmann SL, Ekins S, Sands MS, Wishart TM, Cooper JD. Nelvagal HR, et al. Among authors: tennant p. J Clin Invest. 2022 Oct 17;132(20):e163107. doi: 10.1172/JCI163107. J Clin Invest. 2022. PMID: 36040802 Free PMC article.
Modelling Neurological Diseases in Large Animals: Criteria for Model Selection and Clinical Assessment.
Eaton SL, Murdoch F, Rzechorzek NM, Thompson G, Hartley C, Blacklock BT, Proudfoot C, Lillico SG, Tennant P, Ritchie A, Nixon J, Brennan PM, Guido S, Mitchell NL, Palmer DN, Whitelaw CBA, Cooper JD, Wishart TM. Eaton SL, et al. Among authors: tennant p. Cells. 2022 Aug 25;11(17):2641. doi: 10.3390/cells11172641. Cells. 2022. PMID: 36078049 Free PMC article. Review.
A lung segmental model of chronic Pseudomonas infection in sheep.
Collie D, Govan J, Wright S, Thornton E, Tennant P, Smith S, Doherty C, McLachlan G. Collie D, et al. Among authors: tennant p. PLoS One. 2013 Jul 9;8(7):e67677. doi: 10.1371/journal.pone.0067677. Print 2013. PLoS One. 2013. PMID: 23874438 Free PMC article.
Variability of the Sheep Lung Microbiota.
Glendinning L, Wright S, Pollock J, Tennant P, Collie D, McLachlan G. Glendinning L, et al. Among authors: tennant p. Appl Environ Microbiol. 2016 May 16;82(11):3225-3238. doi: 10.1128/AEM.00540-16. Print 2016 Jun 1. Appl Environ Microbiol. 2016. PMID: 26994083 Free PMC article.
Microbiota in Exhaled Breath Condensate and the Lung.
Glendinning L, Wright S, Tennant P, Gill AC, Collie D, McLachlan G. Glendinning L, et al. Among authors: tennant p. Appl Environ Microbiol. 2017 May 31;83(12):e00515-17. doi: 10.1128/AEM.00515-17. Print 2017 Jun 15. Appl Environ Microbiol. 2017. PMID: 28389539 Free PMC article.
Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.
McLachlan G, Davidson H, Holder E, Davies LA, Pringle IA, Sumner-Jones SG, Baker A, Tennant P, Gordon C, Vrettou C, Blundell R, Hyndman L, Stevenson B, Wilson A, Doherty A, Shaw DJ, Coles RL, Painter H, Cheng SH, Scheule RK, Davies JC, Innes JA, Hyde SC, Griesenbach U, Alton EW, Boyd AC, Porteous DJ, Gill DR, Collie DD. McLachlan G, et al. Among authors: tennant p. Gene Ther. 2011 Oct;18(10):996-1005. doi: 10.1038/gt.2011.55. Epub 2011 Apr 21. Gene Ther. 2011. PMID: 21512505
Optimizing aerosol gene delivery and expression in the ovine lung.
McLachlan G, Baker A, Tennant P, Gordon C, Vrettou C, Renwick L, Blundell R, Cheng SH, Scheule RK, Davies L, Painter H, Coles RL, Lawton AE, Marriott C, Gill DR, Hyde SC, Griesenbach U, Alton EW, Boyd AC, Porteous DJ, Collie DD. McLachlan G, et al. Among authors: tennant p. Mol Ther. 2007 Feb;15(2):348-54. doi: 10.1038/sj.mt.6300058. Mol Ther. 2007. PMID: 17235313 Free article.
The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep.
Alton EW, Baker A, Baker E, Boyd AC, Cheng SH, Coles RL, Collie DD, Davidson H, Davies JC, Gill DR, Gordon C, Griesenbach U, Higgins T, Hyde SC, Innes JA, McCormick D, McGovern M, McLachlan G, Porteous DJ, Pringle I, Scheule RK, Shaw DJ, Smith S, Sumner-Jones SG, Tennant P, Vrettou C. Alton EW, et al. Among authors: tennant p. Biomaterials. 2013 Dec;34(38):10267-77. doi: 10.1016/j.biomaterials.2013.09.023. Epub 2013 Oct 3. Biomaterials. 2013. PMID: 24090839
Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer.
Griesenbach U, Vicente CC, Roberts MJ, Meng C, Soussi S, Xenariou S, Tennant P, Baker A, Baker E, Gordon C, Vrettou C, McCormick D, Coles R, Green AM, Lawton AE, Sumner-Jones SG, Cheng SH, Scheule RK, Hyde SC, Gill DR, Collie DD, McLachlan G, Alton EW. Griesenbach U, et al. Among authors: tennant p. Biomaterials. 2011 Apr;32(10):2614-24. doi: 10.1016/j.biomaterials.2010.12.001. Epub 2011 Jan 15. Biomaterials. 2011. PMID: 21239054 Free article.
121 results