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Page 1
Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates.
Gagne M, Flynn BJ, Andrew SF, Flebbe DR, Mychalowych A, Lamb E, Davis-Gardner ME, Burnett MR, Serebryannyy LA, Lin BC, Pessaint L, Todd JM, Ziff ZE, Maule E, Carroll R, Naisan M, Jethmalani Y, Case JB, Dmitriev IP, Kashentseva EA, Ying B, Dodson A, Kouneski K, Doria-Rose NA, O'Dell S, Godbole S, Laboune F, Henry AR, Marquez J, Teng IT, Wang L, Zhou Q, Wali B, Ellis M, Zouantchangadou S, Ry AV, Lewis MG, Andersen H, Kwong PD, Curiel DT, Foulds KE, Nason MC, Suthar MS, Roederer M, Diamond MS, Douek DC, Seder RA. Gagne M, et al. Among authors: teng it. bioRxiv [Preprint]. 2023 Nov 8:2023.11.06.565765. doi: 10.1101/2023.11.06.565765. bioRxiv. 2023. PMID: 37986823 Free PMC article. Preprint.
Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.
Shi W, Wang L, Zhou T, Sastry M, Yang ES, Zhang Y, Chen M, Chen X, Choe M, Creanga A, Leung K, Olia AS, Pegu A, Rawi R, Shen CH, Stancofski ED, Talana CA, Teng IT, Wang S, Corbett KS, Tsybovsky Y, Mascola JR, Kwong PD. Shi W, et al. Among authors: teng it. bioRxiv [Preprint]. 2022 Jan 26:2022.01.25.477770. doi: 10.1101/2022.01.25.477770. bioRxiv. 2022. PMID: 35118472 Free PMC article. Updated. Preprint.
Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.
Lima NS, Musayev M, Johnston TS, Wagner DA, Henry AR, Wang L, Yang ES, Zhang Y, Birungi K, Black WP, O'Dell S, Schmidt SD, Moon D, Lorang CG, Zhao B, Chen M, Boswell KL, Roberts-Torres J, Davis RL, Peyton L, Narpala SR, O'Connell S, Wang J, Schrager A, Talana CA, Leung K, Shi W, Khashab R, Biber A, Zilberman T, Rhein J, Vetter S, Ahmed A, Novik L, Widge A, Gordon I, Guech M, Teng IT, Phung E, Ruckwardt TJ, Pegu A, Misasi J, Doria-Rose NA, Gaudinski M, Koup RA, Kwong PD, McDermott AB, Amit S, Schacker TW, Levy I, Mascola JR, Sullivan NJ, Schramm CA, Douek DC. Lima NS, et al. Among authors: teng it. bioRxiv [Preprint]. 2022 Jun 30:2022.03.28.486152. doi: 10.1101/2022.03.28.486152. bioRxiv. 2022. PMID: 35378757 Free PMC article. Updated. Preprint.
Recent SARS-CoV-2 infection abrogates antibody and B-cell responses to booster vaccination.
Buckner CM, Kardava L, Merhebi OE, Narpala SR, Serebryannyy L, Lin BC, Wang W, Zhang X, de Assis FL, Kelly SEM, Teng IT, McCormack GE, Praiss LH, Seamon CA, Rai MA, Kalish H, Kwong PD, Proschan MA, McDermott AB, Fauci AS, Chun TW, Moir S. Buckner CM, et al. Among authors: teng it. medRxiv [Preprint]. 2022 Aug 31:2022.08.30.22279344. doi: 10.1101/2022.08.30.22279344. medRxiv. 2022. PMID: 36093348 Free PMC article. Updated. Preprint.
A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Chonira V, Kwon YD, Gorman J, Case JB, Ku Z, Simeon R, Casner RG, Harris DR, Olia AS, Stephens T, Shapiro L, Bender MF, Boyd H, Teng IT, Tsybovsky Y, Krammer F, Zhang N, Diamond MS, Kwong PD, An Z, Chen Z. Chonira V, et al. Among authors: teng it. Nat Chem Biol. 2023 Mar;19(3):284-291. doi: 10.1038/s41589-022-01193-2. Epub 2022 Nov 21. Nat Chem Biol. 2023. PMID: 36411391 Free PMC article.
RBD-based high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways.
Gagne M, Flynn BJ, Honeycutt CC, Flebbe DR, Andrew SF, Provost SJ, McCormick L, Van Ry A, McCarthy E, Todd JM, Bao S, Teng IT, Marciano S, Rudich Y, Li C, Pessaint L, Dodson A, Cook A, Lewis MG, Andersen H, Zahradník J, Nason MC, Foulds KE, Kwong PD, Roederer M, Schreiber G, Seder RA, Douek DC. Gagne M, et al. Among authors: teng it. bioRxiv [Preprint]. 2023 Jun 12:2023.06.09.544432. doi: 10.1101/2023.06.09.544432. bioRxiv. 2023. PMID: 37503026 Free PMC article. Preprint.
XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants.
Jain S, Kumar S, Lai L, Linderman S, Malik AA, Ellis ML, Godbole S, Solis D, Sahoo MK, Bechnak K, Paredes I, Tanios R, Kazzi B, Dib SM, Litvack MB, Wimalasena ST, Ciric C, Rostad C, West R, Teng IT, Wang D, Edupuganti S, Kwong PD, Rouphael N, Pinsky BA, Douek DC, Wrammert J, Moreno A, Suthar MS. Jain S, et al. Among authors: teng it. bioRxiv [Preprint]. 2024 Feb 5:2024.02.03.578771. doi: 10.1101/2024.02.03.578771. bioRxiv. 2024. PMID: 38370837 Free PMC article. Preprint.
Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques.
Buchholz U, Kaiser J, Nelson C, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Ahlers L, Herbert R, Moore I, Wilder-Kofie T, Moore R, Walker A, Lijuan Y, Munir S, Teng IT, Kwong P, Dowdell K, Nguyen H, Kim J, Cohen J, Johnson RF, Garza N, Via L, Barber D, LE Nouen C. Buchholz U, et al. Among authors: teng it. Res Sq [Preprint]. 2023 Sep 13:rs.3.rs-3278289. doi: 10.21203/rs.3.rs-3278289/v1. Res Sq. 2023. PMID: 37790295 Free PMC article. Updated. Preprint.
Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA.5.
Wang Z, Zhang B, Ou L, Qiu Q, Wang L, Bylund T, Kong WP, Shi W, Tsybovsky Y, Wu L, Zhou Q, Chaudhary R, Choe M, Dickey TH, El Anbari M, Olia AS, Rawi R, Teng IT, Wang D, Wang S, Tolia NH, Zhou T, Kwong PD. Wang Z, et al. Among authors: teng it. Vaccines (Basel). 2023 Dec 28;12(1):37. doi: 10.3390/vaccines12010037. Vaccines (Basel). 2023. PMID: 38250850 Free PMC article.
Long trimer-immunization interval and appropriate adjuvant reduce immune responses to the soluble HIV-1-envelope trimer base.
Duan H, Corrigan AR, Cheng C, Biju A, Gonelli CA, Olia AS, Teng IT, Xu K, O'Dell S, Narpala S, Castro M, Serebryannyy L, Wang J, Parchment DK, Sarfo EK, van Schooten J, Todd JP, Wang S, Harris DR, Geng H, Jafari AJ; VRC Production Program; Woodward RA, Doria-Rose NA, Foulds KE, McDermott AB, van Gils MJ, Koup RA, Pierson TC, Kwong PD, Mascola JR. Duan H, et al. Among authors: teng it. iScience. 2024 Jan 11;27(2):108877. doi: 10.1016/j.isci.2024.108877. eCollection 2024 Feb 16. iScience. 2024. PMID: 38318357 Free PMC article.
73 results