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Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.
Krawczyk PM, Eppink B, Essers J, Stap J, Rodermond H, Odijk H, Zelensky A, van Bree C, Stalpers LJ, Buist MR, Soullié T, Rens J, Verhagen HJ, O'Connor MJ, Franken NA, Ten Hagen TL, Kanaar R, Aten JA. Krawczyk PM, et al. Among authors: ten hagen tl. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9851-6. doi: 10.1073/pnas.1101053108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555554 Free PMC article.
A novel two-step mild hyperthermia for advanced liposomal chemotherapy.
Li L, ten Hagen TL, Haeri A, Soullié T, Scholten C, Seynhaeve AL, Eggermont AM, Koning GA. Li L, et al. Among authors: ten hagen tl. J Control Release. 2014 Jan 28;174:202-8. doi: 10.1016/j.jconrel.2013.11.012. Epub 2013 Nov 22. J Control Release. 2014. PMID: 24269966
Plasma membrane targeting by short chain sphingolipids inserted in liposomes improves anti-tumor activity of mitoxantrone in an orthotopic breast carcinoma xenograft model.
Cordeiro Pedrosa LR, van Tellingen O, Soullié T, Seynhaeve AL, Eggermont AM, Ten Hagen TL, Verheij M, Koning GA. Cordeiro Pedrosa LR, et al. Among authors: ten hagen tl. Eur J Pharm Biopharm. 2015 Aug;94:207-19. doi: 10.1016/j.ejpb.2015.05.003. Epub 2015 May 14. Eur J Pharm Biopharm. 2015. PMID: 25982691
206 results