Templeton AC - Search Results

1

Strategies for bringing drug delivery tools into discovery.

Kwong E, Higgins J, Templeton AC. Kwong E, et al. Among authors: templeton ac. Int J Pharm. 2011 Jun 30;412(1-2):1-7. doi: 10.1016/j.ijpharm.2011.03.024. Epub 2011 Mar 21. Int J Pharm. 2011. PMID: 21421040 Review.

2

Spectroscopic approach for on-line monitoring of particle size during the processing of pharmaceutical nanoparticles.

Higgins JP, Arrivo SM, Thurau G, Green RL, Bowen W, Lange A, Templeton AC, Thomas DL, Reed RA. Higgins JP, et al. Among authors: templeton ac. Anal Chem. 2003 Apr 15;75(8):1777-85. doi: 10.1021/ac0207980. Anal Chem. 2003. PMID: 12713033

3

Strategies at the interface of drug discovery and development: early optimization of the solid state phase and preclinical toxicology formulation for potential drug candidates.

Palucki M, Higgins JD, Kwong E, Templeton AC. Palucki M, et al. Among authors: templeton ac. J Med Chem. 2010 Aug 26;53(16):5897-905. doi: 10.1021/jm1002638. J Med Chem. 2010. PMID: 20527889 No abstract available.

4

Progressing preclinical drug candidates: strategies on preclinical safety studies and the quest for adequate exposure.

Higgins J, Cartwright ME, Templeton AC. Higgins J, et al. Among authors: templeton ac. Drug Discov Today. 2012 Aug;17(15-16):828-36. doi: 10.1016/j.drudis.2012.03.016. Epub 2012 Apr 11. Drug Discov Today. 2012. PMID: 22546604 Review.

5

Correlation between molecular mobility and physical stability of amorphous itraconazole.

Bhardwaj SP, Arora KK, Kwong E, Templeton A, Clas SD, Suryanarayanan R. Bhardwaj SP, et al. Mol Pharm. 2013 Feb 4;10(2):694-700. doi: 10.1021/mp300487u. Epub 2013 Jan 8. Mol Pharm. 2013. PMID: 23198856

6

Design of prodrugs to enhance colonic absorption by increasing lipophilicity and blocking ionization.

Nofsinger R, Clas SD, Sanchez RI, Walji A, Manser K, Nissley B, Balsells J, Nair A, Dang Q, Bennett DJ, Hafey M, Wang J, Higgins J, Templeton A, Coleman P, Grobler J, Smith R, Wu Y. Nofsinger R, et al. Pharmaceuticals (Basel). 2014 Feb 24;7(2):207-19. doi: 10.3390/ph7020207. Pharmaceuticals (Basel). 2014. PMID: 24566521 Free PMC article.

7

Mechanism of amorphous itraconazole stabilization in polymer solid dispersions: role of molecular mobility.

Bhardwaj SP, Arora KK, Kwong E, Templeton A, Clas SD, Suryanarayanan R. Bhardwaj SP, et al. Mol Pharm. 2014 Nov 3;11(11):4228-37. doi: 10.1021/mp5004515. Epub 2014 Oct 17. Mol Pharm. 2014. PMID: 25325389

8

Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.

Walji AM, Sanchez RI, Clas SD, Nofsinger R, de Lera Ruiz M, Li J, Bennet A, John C, Bennett DJ, Sanders JM, Di Marco CN, Kim SH, Balsells J, Ceglia SS, Dang Q, Manser K, Nissley B, Wai JS, Hafey M, Wang J, Chessen G, Templeton A, Higgins J, Smith R, Wu Y, Grobler J, Coleman PJ. Walji AM, et al. ChemMedChem. 2015 Feb;10(2):245-52. doi: 10.1002/cmdc.201402393. Epub 2014 Dec 2. ChemMedChem. 2015. PMID: 25469982

9

Design of experiments utilization to map the processing capabilities of a micro-spray dryer: particle design and throughput optimization in support of drug discovery.

Ormes JD, Zhang D, Chen AM, Hou S, Krueger D, Nelson T, Templeton A. Ormes JD, et al. Pharm Dev Technol. 2013 Feb;18(1):121-9. doi: 10.3109/10837450.2011.646424. Epub 2012 Mar 14. Pharm Dev Technol. 2013. PMID: 22414114

10

New and Evolving Techniques for the Characterization of Peptide Therapeutics.

D'Addio SM, Bothe JR, Neri C, Walsh PL, Zhang J, Pierson E, Mao Y, Gindy M, Leone A, Templeton AC. D'Addio SM, et al. Among authors: templeton ac. J Pharm Sci. 2016 Oct;105(10):2989-3006. doi: 10.1016/j.xphs.2016.06.011. Epub 2016 Aug 4. J Pharm Sci. 2016. PMID: 27499338 Review.

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