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APOBEC3B is an enzymatic source of mutation in breast cancer.
Burns MB, Lackey L, Carpenter MA, Rathore A, Land AM, Leonard B, Refsland EW, Kotandeniya D, Tretyakova N, Nikas JB, Yee D, Temiz NA, Donohue DE, McDougle RM, Brown WL, Law EK, Harris RS. Burns MB, et al. Among authors: temiz na. Nature. 2013 Feb 21;494(7437):366-70. doi: 10.1038/nature11881. Epub 2013 Feb 6. Nature. 2013. PMID: 23389445 Free PMC article.
Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases.
Durfee C, Temiz NA, Levin-Klein R, Argyris PP, Alsøe L, Carracedo S, de la Vega AA, Proehl J, Holzhauer AM, Seeman ZJ, Lin YT, Vogel RI, Sotillo R, Nilsen H, Harris RS. Durfee C, et al. Among authors: temiz na. bioRxiv [Preprint]. 2023 Feb 25:2023.02.24.529970. doi: 10.1101/2023.02.24.529970. bioRxiv. 2023. PMID: 36865194 Free PMC article. Updated. Preprint.
DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo.
Naumann JA, Argyris PP, Carpenter MA, Gupta HB, Chen Y, Temiz NA, Zhou Y, Durfee C, Proehl J, Koniar BL, Conticello SG, Largaespada DA, Brown WL, Aihara H, Vogel RI, Harris RS. Naumann JA, et al. Among authors: temiz na. Int J Mol Sci. 2023 May 26;24(11):9305. doi: 10.3390/ijms24119305. Int J Mol Sci. 2023. PMID: 37298259 Free PMC article.
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.
McCann JL, Cristini A, Law EK, Lee SY, Tellier M, Carpenter MA, Beghè C, Kim JJ, Sanchez A, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM, Gromak N, Harris RS. McCann JL, et al. Among authors: temiz na. Nat Genet. 2023 Oct;55(10):1721-1734. doi: 10.1038/s41588-023-01504-w. Epub 2023 Sep 21. Nat Genet. 2023. PMID: 37735199 Free PMC article.
45 results