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Mutation Signatures Including APOBEC in Cancer Cell Lines.
Jarvis MC, Ebrahimi D, Temiz NA, Harris RS. Jarvis MC, et al. Among authors: temiz na. JNCI Cancer Spectr. 2018 Jan;2(1):pky002. doi: 10.1093/jncics/pky002. Epub 2018 Mar 17. JNCI Cancer Spectr. 2018. PMID: 29888758 Free PMC article.
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
Law EK, Levin-Klein R, Jarvis MC, Kim H, Argyris PP, Carpenter MA, Starrett GJ, Temiz NA, Larson LK, Durfee C, Burns MB, Vogel RI, Stavrou S, Aguilera AN, Wagner S, Largaespada DA, Starr TK, Ross SR, Harris RS. Law EK, et al. Among authors: temiz na. J Exp Med. 2020 Dec 7;217(12):e20200261. doi: 10.1084/jem.20200261. J Exp Med. 2020. PMID: 32870257 Free PMC article.
Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases.
Durfee C, Temiz NA, Levin-Klein R, Argyris PP, Alsøe L, Carracedo S, de la Vega AA, Proehl J, Holzhauer AM, Seeman ZJ, Lin YT, Vogel RI, Sotillo R, Nilsen H, Harris RS. Durfee C, et al. Among authors: temiz na. bioRxiv [Preprint]. 2023 Feb 25:2023.02.24.529970. doi: 10.1101/2023.02.24.529970. bioRxiv. 2023. PMID: 36865194 Free PMC article. Updated. Preprint.
DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo.
Naumann JA, Argyris PP, Carpenter MA, Gupta HB, Chen Y, Temiz NA, Zhou Y, Durfee C, Proehl J, Koniar BL, Conticello SG, Largaespada DA, Brown WL, Aihara H, Vogel RI, Harris RS. Naumann JA, et al. Among authors: temiz na. Int J Mol Sci. 2023 May 26;24(11):9305. doi: 10.3390/ijms24119305. Int J Mol Sci. 2023. PMID: 37298259 Free PMC article.
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.
McCann JL, Cristini A, Law EK, Lee SY, Tellier M, Carpenter MA, Beghè C, Kim JJ, Sanchez A, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM, Gromak N, Harris RS. McCann JL, et al. Among authors: temiz na. Nat Genet. 2023 Oct;55(10):1721-1734. doi: 10.1038/s41588-023-01504-w. Epub 2023 Sep 21. Nat Genet. 2023. PMID: 37735199 Free PMC article.
45 results