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Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study.
Prasch H, Wolfsgruber A, Thonhofer M, Culum A, Mandl C, Weber P, Zündel M, Nasseri SA, Gonzalez Santana A, Tegl G, Nidetzky B, Gruber K, Stütz AE, Withers SG, Wrodnigg TM. Prasch H, et al. Among authors: tegl g. Chembiochem. 2023 Dec 1;24(23):e202300480. doi: 10.1002/cbic.202300480. Epub 2023 Oct 10. Chembiochem. 2023. PMID: 37715738
A Synthetic Gene Library Yields a Previously Unknown Glycoside Phosphorylase That Degrades and Assembles Poly-β-1,3-GlcNAc, Completing the Suite of β-Linked GlcNAc Polysaccharides.
Macdonald SS, Pereira JH, Liu F, Tegl G, DeGiovanni A, Wardman JF, Deutsch S, Yoshikuni Y, Adams PD, Withers SG. Macdonald SS, et al. Among authors: tegl g. ACS Cent Sci. 2022 Apr 27;8(4):430-440. doi: 10.1021/acscentsci.1c01570. Epub 2022 Mar 16. ACS Cent Sci. 2022. PMID: 35505869 Free PMC article.
Corrigendum: Facile Formation of β-thioGlcNAc Linkages to Thiol-Containing Sugars, Peptides, and Proteins using a Mutant GH20 Hexosaminidase.
Zhao J, Si Y, Han Z, Li J, Guo W, Fu Y, Tegl G, Hanson J, Chen HM, Kwan DH, Santana AG, Withers SG. Zhao J, et al. Among authors: tegl g. Angew Chem Int Ed Engl. 2020 Jun 2;59(23):8752. doi: 10.1002/anie.202001582. Epub 2020 Mar 18. Angew Chem Int Ed Engl. 2020. PMID: 32449594 Free PMC article. No abstract available.
21 results