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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.
Tan TK, Rijal P, Rahikainen R, Keeble AH, Schimanski L, Hussain S, Harvey R, Hayes JWP, Edwards JC, McLean RK, Martini V, Pedrera M, Thakur N, Conceicao C, Dietrich I, Shelton H, Ludi A, Wilsden G, Browning C, Zagrajek AK, Bialy D, Bhat S, Stevenson-Leggett P, Hollinghurst P, Tully M, Moffat K, Chiu C, Waters R, Gray A, Azhar M, Mioulet V, Newman J, Asfor AS, Burman A, Crossley S, Hammond JA, Tchilian E, Charleston B, Bailey D, Tuthill TJ, Graham SP, Duyvesteyn HME, Malinauskas T, Huo J, Tree JA, Buttigieg KR, Owens RJ, Carroll MW, Daniels RS, McCauley JW, Stuart DI, Huang KA, Howarth M, Townsend AR. Tan TK, et al. Among authors: tchilian e. Nat Commun. 2021 Jan 22;12(1):542. doi: 10.1038/s41467-020-20654-7. Nat Commun. 2021. PMID: 33483491 Free PMC article.
Therapeutic Administration of Broadly Neutralizing FI6 Antibody Reveals Lack of Interaction Between Human IgG1 and Pig Fc Receptors.
Morgan SB, Holzer B, Hemmink JD, Salguero FJ, Schwartz JC, Agatic G, Cameroni E, Guarino B, Porter E, Rijal P, Townsend A, Charleston B, Corti D, Tchilian E. Morgan SB, et al. Among authors: tchilian e. Front Immunol. 2018 Apr 24;9:865. doi: 10.3389/fimmu.2018.00865. eCollection 2018. Front Immunol. 2018. PMID: 29740451 Free PMC article.
Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig.
Tungatt K, Dolton G, Morgan SB, Attaf M, Fuller A, Whalley T, Hemmink JD, Porter E, Szomolay B, Montoya M, Hammond JA, Miles JJ, Cole DK, Townsend A, Bailey M, Rizkallah PJ, Charleston B, Tchilian E, Sewell AK. Tungatt K, et al. Among authors: tchilian e. PLoS Pathog. 2018 May 17;14(5):e1007017. doi: 10.1371/journal.ppat.1007017. eCollection 2018 May. PLoS Pathog. 2018. PMID: 29772011 Free PMC article.
T and B Cell Immune Responses to Influenza Viruses in Pigs.
Holzer B, Martini V, Edmans M, Tchilian E. Holzer B, et al. Among authors: tchilian e. Front Immunol. 2019 Feb 5;10:98. doi: 10.3389/fimmu.2019.00098. eCollection 2019. Front Immunol. 2019. PMID: 30804933 Free PMC article. Review.
Vaccine-mediated protection of pigs against infection with pandemic H1N1 2009 swine influenza A virus requires a close antigenic match between the vaccine antigen and challenge virus.
Everett HE, Aramouni M, Coward V, Ramsay A, Kelly M, Morgan S, Tchilian E, Canini L, Woolhouse MEJ, Gilbert S, Charleston B, Brown IH, Brookes SM. Everett HE, et al. Among authors: tchilian e. Vaccine. 2019 Apr 17;37(17):2288-2293. doi: 10.1016/j.vaccine.2019.02.078. Epub 2019 Mar 23. Vaccine. 2019. PMID: 30914224 Free PMC article.
90 results