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Oncogenic MYC amplifies mitotic perturbations.
Littler S, Sloss O, Geary B, Pierce A, Whetton AD, Taylor SS. Littler S, et al. Among authors: taylor ss. Open Biol. 2019 Aug 30;9(8):190136. doi: 10.1098/rsob.190136. Epub 2019 Aug 28. Open Biol. 2019. PMID: 31455158 Free PMC article.
GSK-3 inhibitors induce chromosome instability.
Tighe A, Ray-Sinha A, Staples OD, Taylor SS. Tighe A, et al. Among authors: taylor ss. BMC Cell Biol. 2007 Aug 14;8:34. doi: 10.1186/1471-2121-8-34. BMC Cell Biol. 2007. PMID: 17697341 Free PMC article.
Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.
Matthews LC, Berry AA, Morgan DJ, Poolman TM, Bauer K, Kramer F, Spiller DG, Richardson RV, Chapman KE, Farrow SN, Norman MR, Williamson AJ, Whetton AD, Taylor SS, Tuckermann JP, White MR, Ray DW. Matthews LC, et al. Among authors: taylor ss. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5479-84. doi: 10.1073/pnas.1411356112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25847991 Free PMC article.
MYC Is a Major Determinant of Mitotic Cell Fate.
Topham C, Tighe A, Ly P, Bennett A, Sloss O, Nelson L, Ridgway RA, Huels D, Littler S, Schandl C, Sun Y, Bechi B, Procter DJ, Sansom OJ, Cleveland DW, Taylor SS. Topham C, et al. Among authors: taylor ss. Cancer Cell. 2015 Jul 13;28(1):129-40. doi: 10.1016/j.ccell.2015.06.001. Cancer Cell. 2015. PMID: 26175417 Free PMC article.
The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α.
Simões-Sousa S, Littler S, Thompson SL, Minshall P, Whalley H, Bakker B, Belkot K, Moralli D, Bronder D, Tighe A, Spierings DCJ, Bah N, Graham J, Nelson L, Green CM, Foijer F, Townsend PA, Taylor SS. Simões-Sousa S, et al. Among authors: taylor ss. Cell Rep. 2018 Oct 16;25(3):749-760.e6. doi: 10.1016/j.celrep.2018.09.060. Cell Rep. 2018. PMID: 30332653 Free PMC article.
DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors.
Pillay N, Tighe A, Nelson L, Littler S, Coulson-Gilmer C, Bah N, Golder A, Bakker B, Spierings DCJ, James DI, Smith KM, Jordan AM, Morgan RD, Ogilvie DJ, Foijer F, Jackson DA, Taylor SS. Pillay N, et al. Among authors: taylor ss. Cancer Cell. 2019 Mar 18;35(3):519-533.e8. doi: 10.1016/j.ccell.2019.02.004. Cancer Cell. 2019. PMID: 30889383 Free PMC article.
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.
Nelson L, Tighe A, Golder A, Littler S, Bakker B, Moralli D, Murtuza Baker S, Donaldson IJ, Spierings DCJ, Wardenaar R, Neale B, Burghel GJ, Winter-Roach B, Edmondson R, Clamp AR, Jayson GC, Desai S, Green CM, Hayes A, Foijer F, Morgan RD, Taylor SS. Nelson L, et al. Among authors: taylor ss. Nat Commun. 2020 Feb 13;11(1):822. doi: 10.1038/s41467-020-14551-2. Nat Commun. 2020. PMID: 32054838 Free PMC article.
580 results