Taylor P - Search Results

1

Structure-based discovery of a family of synthetic cyclophilin inhibitors showing a cyclosporin-A phenotype in Caenorhabditis elegans.

Yang Y, Moir E, Kontopidis G, Taylor P, Wear MA, Malone K, Dunsmore CJ, Page AP, Turner NJ, Walkinshaw MD. Yang Y, et al. Among authors: taylor p. Biochem Biophys Res Commun. 2007 Nov 30;363(4):1013-9. doi: 10.1016/j.bbrc.2007.09.079. Epub 2007 Oct 1. Biochem Biophys Res Commun. 2007. PMID: 17927958

2

Structural and biological characterisation of the gut-associated cyclophilin B isoforms from Caenorhabditis elegans.

Picken NC, Eschenlauer S, Taylor P, Page AP, Walkinshaw MD. Picken NC, et al. Among authors: taylor p. J Mol Biol. 2002 Sep 6;322(1):15-25. doi: 10.1016/s0022-2836(02)00712-x. J Mol Biol. 2002. PMID: 12215411

3

Selective chemical intervention in the proteome of Caenorhabditis elegans.

Husi H, McAllister F, Angelopoulos N, Butler VJ, Bailey KR, Malone K, Mackay L, Taylor P, Page AP, Turner NJ, Barran PE, Walkinshaw M. Husi H, et al. Among authors: taylor p. J Proteome Res. 2010 Nov 5;9(11):6060-70. doi: 10.1021/pr100427c. Epub 2010 Sep 22. J Proteome Res. 2010. PMID: 20804218

4

Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans.

Dornan J, Page AP, Taylor P, Wu Sy, Winter AD, Husi H, Walkinshaw MD. Dornan J, et al. Among authors: taylor p. J Biol Chem. 1999 Dec 3;274(49):34877-83. doi: 10.1074/jbc.274.49.34877. J Biol Chem. 1999. PMID: 10574961 Free article.

5

Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop.

Wu SY, McNae I, Kontopidis G, McClue SJ, McInnes C, Stewart KJ, Wang S, Zheleva DI, Marriage H, Lane DP, Taylor P, Fischer PM, Walkinshaw MD. Wu SY, et al. Among authors: taylor p. Structure. 2003 Apr;11(4):399-410. doi: 10.1016/s0969-2126(03)00060-1. Structure. 2003. PMID: 12679018 Free article.

6

Structures of immunophilins and their ligand complexes.

Dornan J, Taylor P, Walkinshaw MD. Dornan J, et al. Among authors: taylor p. Curr Top Med Chem. 2003;3(12):1392-409. doi: 10.2174/1568026033451899. Curr Top Med Chem. 2003. PMID: 12871171 Review.

7

Enzymatic and structural characterization of non-peptide ligand-cyclophilin complexes.

Kontopidis G, Taylor P, Walkinshaw MD. Kontopidis G, et al. Among authors: taylor p. Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):479-85. doi: 10.1107/S0907444904000174. Epub 2004 Feb 25. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 14993672 Free article.

8

Identification of protein binding surfaces using surface triplet propensities.

Mehio W, Kemp GJ, Taylor P, Walkinshaw MD. Mehio W, et al. Among authors: taylor p. Bioinformatics. 2010 Oct 15;26(20):2549-55. doi: 10.1093/bioinformatics/btq490. Epub 2010 Sep 6. Bioinformatics. 2010. PMID: 20819959

9

A Molecular Dynamics Study of Allosteric Transitions in Leishmania mexicana Pyruvate Kinase.

Naithani A, Taylor P, Erman B, Walkinshaw MD. Naithani A, et al. Among authors: taylor p. Biophys J. 2015 Sep 15;109(6):1149-56. doi: 10.1016/j.bpj.2015.05.040. Epub 2015 Jul 22. Biophys J. 2015. PMID: 26210208 Free PMC article.

10

An example of a protein ligand found by database mining: description of the docking method and its verification by a 2.3 A X-ray structure of a thrombin-ligand complex.

Burkhard P, Taylor P, Walkinshaw MD. Burkhard P, et al. Among authors: taylor p. J Mol Biol. 1998 Mar 27;277(2):449-66. doi: 10.1006/jmbi.1997.1608. J Mol Biol. 1998. PMID: 9514757

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