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Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens.
Wang Y, Fan JL, Melms JC, Amin AD, Georgis Y, Barrera I, Ho P, Tagore S, Abril-Rodríguez G, He S, Jin Y, Biermann J, Hofree M, Caprio L, Berhe S, Khan SA, Henick BS, Ribas A, Macosko EZ, Chen F, Taylor AM, Schwartz GK, Carvajal RD, Azizi E, Izar B. Wang Y, et al. Among authors: taylor am. Nat Genet. 2023 Jan;55(1):19-25. doi: 10.1038/s41588-022-01268-9. Epub 2023 Jan 9. Nat Genet. 2023. PMID: 36624340 Free PMC article.
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Viswanathan SR, Nogueira MF, Buss CG, Krill-Burger JM, Wawer MJ, Malolepsza E, Berger AC, Choi PS, Shih J, Taylor AM, Tanenbaum B, Pedamallu CS, Cherniack AD, Tamayo P, Strathdee CA, Lage K, Carr SA, Schenone M, Bhatia SN, Vazquez F, Tsherniak A, Hahn WC, Meyerson M. Viswanathan SR, et al. Among authors: taylor am. Nat Genet. 2018 Jul;50(7):937-943. doi: 10.1038/s41588-018-0155-3. Epub 2018 Jun 28. Nat Genet. 2018. PMID: 29955178 Free PMC article.
Genomic and immune profiling of pre-invasive lung adenocarcinoma.
Chen H, Carrot-Zhang J, Zhao Y, Hu H, Freeman SS, Yu S, Ha G, Taylor AM, Berger AC, Westlake L, Zheng Y, Zhang J, Ramachandran A, Zheng Q, Pan Y, Zheng D, Zheng S, Cheng C, Kuang M, Zhou X, Zhang Y, Li H, Ye T, Ma Y, Gao Z, Tao X, Han H, Shang J, Yu Y, Bao D, Huang Y, Li X, Zhang Y, Xiang J, Sun Y, Li Y, Cherniack AD, Campbell JD, Shi L, Meyerson M. Chen H, et al. Among authors: taylor am. Nat Commun. 2019 Nov 29;10(1):5472. doi: 10.1038/s41467-019-13460-3. Nat Commun. 2019. PMID: 31784532 Free PMC article.
Whole-genome doubling confers unique genetic vulnerabilities on tumour cells.
Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Quinton RJ, et al. Among authors: taylor am. Nature. 2021 Feb;590(7846):492-497. doi: 10.1038/s41586-020-03133-3. Epub 2021 Jan 27. Nature. 2021. PMID: 33505027 Free PMC article.
Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer.
Galeano Niño JL, Wu H, LaCourse KD, Kempchinsky AG, Baryiames A, Barber B, Futran N, Houlton J, Sather C, Sicinska E, Taylor A, Minot SS, Johnston CD, Bullman S. Galeano Niño JL, et al. Nature. 2022 Nov;611(7937):810-817. doi: 10.1038/s41586-022-05435-0. Epub 2022 Nov 16. Nature. 2022. PMID: 36385528 Free PMC article.
Molecular Subtypes of Head and Neck Cancer in Patients of African Ancestry.
Mezghani N, Yao A, Vasilyeva D, Kaplan N, Shackelford A, Yoon A, Phillipone E, Dubey S, Schwartz GK, Taylor AM, Momen-Heravi F. Mezghani N, et al. Among authors: taylor am. Clin Cancer Res. 2023 Mar 1;29(5):910-920. doi: 10.1158/1078-0432.CCR-22-2258. Clin Cancer Res. 2023. PMID: 36508165 Free PMC article.
Cancer aneuploidies are shaped primarily by effects on tumour fitness.
Shih J, Sarmashghi S, Zhakula-Kostadinova N, Zhang S, Georgis Y, Hoyt SH, Cuoco MS, Gao GF, Spurr LF, Berger AC, Ha G, Rendo V, Shen H, Meyerson M, Cherniack AD, Taylor AM, Beroukhim R. Shih J, et al. Among authors: taylor am. Nature. 2023 Jul;619(7971):793-800. doi: 10.1038/s41586-023-06266-3. Epub 2023 Jun 28. Nature. 2023. PMID: 37380777 Free PMC article.
Controlled Chaos: Parsing Acquired Immunoresistance in Lung Cancer.
Henick BS, Herzberg BO, Concepcion-Crisol CP, Taylor AM. Henick BS, et al. Among authors: taylor am. J Clin Oncol. 2024 Apr 10;42(11):1211-1214. doi: 10.1200/JCO.23.02339. Epub 2024 Feb 29. J Clin Oncol. 2024. PMID: 38422476 No abstract available.
Quantification of aneuploidy in targeted sequencing data using ASCETS.
Spurr LF, Touat M, Taylor AM, Dubuc AM, Shih J, Meredith DM, Pisano WV, Meyerson ML, Ligon KL, Cherniack AD, Li YY, Beroukhim R. Spurr LF, et al. Among authors: taylor am. Bioinformatics. 2021 Aug 25;37(16):2461-2463. doi: 10.1093/bioinformatics/btaa980. Bioinformatics. 2021. PMID: 33247715 Free PMC article.
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