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The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein.
Van Ostade X, Van der Heyden J, Verhee A, Vandekerckhove J, Tavernier J. Van Ostade X, et al. Among authors: tavernier j. Eur J Biochem. 1999 Feb;259(3):954-60. doi: 10.1046/j.1432-1327.1999.00148.x. Eur J Biochem. 1999. PMID: 10092887 Free article.
However, analysis of the effect of this mutant IL-5 on COS-1 cells transfected with both receptor subunits, did not show reduced interaction with the beta c subunit [Tavernier, J., Tuypens, T., Verhee, A., Plaetinck, G., Devos, R., Van der Heyden, J., Guisez, …
However, analysis of the effect of this mutant IL-5 on COS-1 cells transfected with both receptor subunits, did not show reduced interaction …
522 results