Tavares-da-Silva E - Search Results

1

Oxymestane, a cytostatic steroid derivative of exemestane with greater antitumor activity in non-estrogen-dependent cell lines.

Pires AS, Varela CL, Marques IA, Abrantes AM, Gonçalves C, Rodrigues T, Matafome P, Botelho MF, Roleira FMF, Tavares-da-Silva E. Pires AS, et al. Among authors: tavares da silva e. J Steroid Biochem Mol Biol. 2021 Sep;212:105950. doi: 10.1016/j.jsbmb.2021.105950. Epub 2021 Jul 14. J Steroid Biochem Mol Biol. 2021. PMID: 34271024

2

Structure-activity relationships of new A,D-ring modified steroids as aromatase inhibitors: design, synthesis, and biological activity evaluation.

Cepa MM, Tavares da Silva EJ, Correia-da-Silva G, Roleira FM, Teixeira NA. Cepa MM, et al. J Med Chem. 2005 Oct 6;48(20):6379-85. doi: 10.1021/jm050129p. J Med Chem. 2005. PMID: 16190763 Free article.

3

Synthesis and biochemical studies of 17-substituted androst-3-enes and 3,4-epoxyandrostanes as aromatase inhibitors.

Cepa MM, Tavares da Silva EJ, Correia-da-Silva G, Roleira FM, Teixeira NA. Cepa MM, et al. Steroids. 2008 Dec 22;73(14):1409-15. doi: 10.1016/j.steroids.2008.07.001. Epub 2008 Jul 17. Steroids. 2008. PMID: 18691607

4

Molecular mechanisms of aromatase inhibition by new A, D-ring modified steroids.

Cepa M, Correia-da-Silva G, Tavares da Silva EJ, Roleira FM, Hong Y, Chen S, Teixeira NA. Cepa M, et al. Biol Chem. 2008 Sep;389(9):1183-91. doi: 10.1515/BC.2008.134. Biol Chem. 2008. PMID: 18713005

5

5alpha-Androst-3-en-17-one oxime.

Andrade LC, de Almeida MJ, Fernandes Roleira FM, Varela CL, Tavares da Silva EJ. Andrade LC, et al. Acta Crystallogr C. 2008 Sep;64(Pt 9):o508-10. doi: 10.1107/S0108270108023299. Epub 2008 Aug 13. Acta Crystallogr C. 2008. PMID: 18758022

6

New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation.

Varela C, Tavares da Silva EJ, Amaral C, Correia da Silva G, Baptista T, Alcaro S, Costa G, Carvalho RA, Teixeira NA, Roleira FM. Varela C, et al. J Med Chem. 2012 Apr 26;55(8):3992-4002. doi: 10.1021/jm300262w. Epub 2012 Apr 18. J Med Chem. 2012. PMID: 22475216

7

Design, synthesis and biochemical studies of new 7α-allylandrostanes as aromatase inhibitors.

Varela CL, Amaral C, Correia-da-Silva G, Carvalho RA, Teixeira NA, Costa SC, Roleira FM, Tavares-da-Silva EJ. Varela CL, et al. Steroids. 2013 Jul;78(7):662-9. doi: 10.1016/j.steroids.2013.02.016. Epub 2013 Mar 13. Steroids. 2013. PMID: 23499824

8

Development of a new gas chromatography-mass spectrometry (GC-MS) methodology for the evaluation of 5α-reductase activity.

Amaral C, Cunha SC, Fernandes JO, Tavares da Silva E, Roleira FM, Teixeira N, Correia-da-Silva G. Amaral C, et al. Talanta. 2013 Mar 30;107:154-61. doi: 10.1016/j.talanta.2012.12.045. Epub 2013 Jan 2. Talanta. 2013. PMID: 23598206

9

Steroidal aromatase inhibitors inhibit growth of hormone-dependent breast cancer cells by inducing cell cycle arrest and apoptosis.

Amaral C, Varela C, Borges M, Tavares da Silva E, Roleira FMF, Correia-da-Silva G, Teixeira N. Amaral C, et al. Apoptosis. 2013 Nov;18(11):1426-1436. doi: 10.1007/s10495-013-0879-6. Apoptosis. 2013. PMID: 23842740

10

New steroidal 17β-carboxy derivatives present anti-5α-reductase activity and anti-proliferative effects in a human androgen-responsive prostate cancer cell line.

Amaral C, Varela C, Correia-da-Silva G, Tavares da Silva E, Carvalho RA, Costa SC, Cunha SC, Fernandes JO, Teixeira N, Roleira FM. Amaral C, et al. Biochimie. 2013 Nov;95(11):2097-106. doi: 10.1016/j.biochi.2013.07.023. Epub 2013 Aug 9. Biochimie. 2013. PMID: 23933094

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