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Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.
Nat Neurosci. 2021 Jun;24(6):786-798. doi: 10.1038/s41593-021-00851-3. Epub 2021 May 6.
Nat Neurosci. 2021.
PMID: 33958804
Free PMC article.
In Vivo Chimeric Alzheimer's Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons.
Najm R, Zalocusky KA, Zilberter M, Yoon SY, Hao Y, Koutsodendris N, Nelson M, Rao A, Taubes A, Jones EA, Huang Y.
Najm R, et al.
Cell Rep. 2020 Jul 28;32(4):107962. doi: 10.1016/j.celrep.2020.107962.
Cell Rep. 2020.
PMID: 32726626
Free PMC article.
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Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women With Alzheimer's Disease.
Paranjpe MD, Belonwu S, Wang JK, Oskotsky T, Gupta A, Taubes A, Zalocusky KA, Paranjpe I, Glicksberg BS, Huang Y, Sirota M.
Paranjpe MD, et al.
Front Aging Neurosci. 2021 Sep 30;13:735611. doi: 10.3389/fnagi.2021.735611. eCollection 2021.
Front Aging Neurosci. 2021.
PMID: 34658838
Free PMC article.
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Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer's Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions.
Belonwu SA, Li Y, Bunis DG, Rao AA, Solsberg CW, Oskotsky T, Taubes AL, Grone B, Zalocusky KA, Fragiadakis GK, Huang Y, Sirota M.
Belonwu SA, et al. Among authors: taubes al.
Front Aging Neurosci. 2022 Apr 27;14:749991. doi: 10.3389/fnagi.2022.749991. eCollection 2022.
Front Aging Neurosci. 2022.
PMID: 35572130
Free PMC article.
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Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer's disease.
Taubes A, Nova P, Zalocusky KA, Kosti I, Bicak M, Zilberter MY, Hao Y, Yoon SY, Oskotsky T, Pineda S, Chen B, Jones EAA, Choudhary K, Grone B, Balestra ME, Chaudhry F, Paranjpe I, De Freitas J, Koutsodendris N, Chen N, Wang C, Chang W, An A, Glicksberg BS, Sirota M, Huang Y.
Taubes A, et al.
Nat Aging. 2021 Oct;1(10):932-947. doi: 10.1038/s43587-021-00122-7. Epub 2021 Oct 11.
Nat Aging. 2021.
PMID: 36172600
Free PMC article.
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Author Correction: Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer's disease.
Taubes A, Nova P, Zalocusky KA, Kosti I, Bicak M, Zilberter MY, Hao Y, Yoon SY, Oskotsky T, Pineda S, Chen B, Aery Jones EA, Choudhary K, Grone B, Balestra ME, Chaudhry F, Paranjpe I, De Freitas J, Koutsodendris N, Chen N, Wang C, Chang W, An A, Glicksberg BS, Sirota M, Huang Y.
Taubes A, et al.
Nat Aging. 2021 Dec;1(12):1202. doi: 10.1038/s43587-021-00144-1.
Nat Aging. 2021.
PMID: 37117528
No abstract available.
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Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, Kraft TW, Farese RV Jr, Green A, Gan L.
Ward ME, et al.
J Exp Med. 2014 Sep 22;211(10):1937-45. doi: 10.1084/jem.20140214. Epub 2014 Aug 25.
J Exp Med. 2014.
PMID: 25155018
Free PMC article.
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Insights into Computational Drug Repurposing for Neurodegenerative Disease.
Paranjpe MD, Taubes A, Sirota M.
Paranjpe MD, et al.
Trends Pharmacol Sci. 2019 Aug;40(8):565-576. doi: 10.1016/j.tips.2019.06.003. Epub 2019 Jul 17.
Trends Pharmacol Sci. 2019.
PMID: 31326236
Free PMC article.
Review.
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