Taskar K - Search Results

1

Considerations for Industry-Preparing for the FDA Model-Informed Drug Development (MIDD) Paired Meeting Program.

Galluppi GR, Ahamadi M, Bhattacharya S, Budha N, Gheyas F, Li CC, Chen Y, Dosne AG, Kristensen NR, Magee M, Samtani MN, Sinha V, Taskar K, Upreti VV, Yang J, Cook J. Galluppi GR, et al. Among authors: taskar k. Clin Pharmacol Ther. 2024 Mar 22. doi: 10.1002/cpt.3245. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38519861 Review.

2

Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer.

Thomas FC, Taskar K, Rudraraju V, Goda S, Thorsheim HR, Gaasch JA, Mittapalli RK, Palmieri D, Steeg PS, Lockman PR, Smith QR. Thomas FC, et al. Among authors: taskar k. Pharm Res. 2009 Nov;26(11):2486-94. doi: 10.1007/s11095-009-9964-5. Epub 2009 Sep 23. Pharm Res. 2009. PMID: 19774344 Free PMC article.

3

Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer.

Taskar KS, Rudraraju V, Mittapalli RK, Samala R, Thorsheim HR, Lockman J, Gril B, Hua E, Palmieri D, Polli JW, Castellino S, Rubin SD, Lockman PR, Steeg PS, Smith QR. Taskar KS, et al. Pharm Res. 2012 Mar;29(3):770-81. doi: 10.1007/s11095-011-0601-8. Epub 2011 Oct 20. Pharm Res. 2012. PMID: 22011930 Free PMC article.

4

Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer.

Samala R, Thorsheim HR, Goda S, Taskar K, Gril B, Steeg PS, Smith QR. Samala R, et al. Among authors: taskar k. Pharm Res. 2016 Dec;33(12):2904-2919. doi: 10.1007/s11095-016-2012-3. Epub 2016 Aug 19. Pharm Res. 2016. PMID: 27541873 Free PMC article.

5

When special populations intersect with drug-drug interactions: Application of physiologically-based pharmacokinetic modeling in pregnant populations.

Sychterz C, Galetin A, Taskar KS. Sychterz C, et al. Biopharm Drug Dispos. 2021 Apr;42(4):160-177. doi: 10.1002/bdd.2272. Epub 2021 Apr 26. Biopharm Drug Dispos. 2021. PMID: 33759451 Review.

6

Robust physiologically based pharmacokinetic model of rifampicin for predicting drug-drug interactions via P-glycoprotein induction and inhibition in the intestine, liver, and kidney.

Asaumi R, Nunoya KI, Yamaura Y, Taskar KS, Sugiyama Y. Asaumi R, et al. Among authors: taskar ks. CPT Pharmacometrics Syst Pharmacol. 2022 Jul;11(7):919-933. doi: 10.1002/psp4.12807. Epub 2022 Jun 6. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35570332 Free PMC article.

7

Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions.

Taskar KS, Harada I, Alluri RV. Taskar KS, et al. Curr Drug Metab. 2021;22(7):523-531. doi: 10.2174/1389200221999210101233340. Curr Drug Metab. 2021. PMID: 33397250 Review.

8

Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat.

Taskar KS, Mariappan TT, Kurawattimath V, Singh Gautam S, Radhakrishna Mullapudi TV, Sridhar SK, Kallem RR, Marathe P, Mandlekar S. Taskar KS, et al. J Cent Nerv Syst Dis. 2017 Mar 15;9:1179573517693596. doi: 10.1177/1179573517693596. eCollection 2017. J Cent Nerv Syst Dis. 2017. PMID: 28469522 Free PMC article.

9

Innovations, Opportunities, and Challenges for Predicting Alteration in Drug-Metabolizing Enzyme and Transporter Activity in Specific Populations.

Chothe PP, Arya V, Prasad B, Ramsden D, Taskar K. Chothe PP, et al. Among authors: taskar k. Drug Metab Dispos. 2023 Dec;51(12):1547-1550. doi: 10.1124/dmd.123.001453. Epub 2023 Sep 29. Drug Metab Dispos. 2023. PMID: 37775331 Free PMC article.

10

Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.

Lockman PR, Mittapalli RK, Taskar KS, Rudraraju V, Gril B, Bohn KA, Adkins CE, Roberts A, Thorsheim HR, Gaasch JA, Huang S, Palmieri D, Steeg PS, Smith QR. Lockman PR, et al. Among authors: taskar ks. Clin Cancer Res. 2010 Dec 1;16(23):5664-78. doi: 10.1158/1078-0432.CCR-10-1564. Epub 2010 Sep 9. Clin Cancer Res. 2010. PMID: 20829328 Free PMC article.

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