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p53 prevents entry into mitosis with uncapped telomeres.
Thanasoula M, Escandell JM, Martinez P, Badie S, Muñoz P, Blasco MA, Tarsounas M. Thanasoula M, et al. Among authors: tarsounas m. Curr Biol. 2010 Mar 23;20(6):521-6. doi: 10.1016/j.cub.2010.01.046. Epub 2010 Mar 11. Curr Biol. 2010. PMID: 20226664 Free PMC article.
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, Hiddingh S, Thanasoula M, Kulkarni A, Yang Q, Haffty BG, Tommiska J, Blomqvist C, Drapkin R, Adams DJ, Nevanlinna H, Bartek J, Tarsounas M, Ganesan S, Jonkers J. Bouwman P, et al. Among authors: tarsounas m. Nat Struct Mol Biol. 2010 Jun;17(6):688-95. doi: 10.1038/nsmb.1831. Epub 2010 May 9. Nat Struct Mol Biol. 2010. PMID: 20453858 Free PMC article.
BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
Badie S, Escandell JM, Bouwman P, Carlos AR, Thanasoula M, Gallardo MM, Suram A, Jaco I, Benitez J, Herbig U, Blasco MA, Jonkers J, Tarsounas M. Badie S, et al. Among authors: tarsounas m. Nat Struct Mol Biol. 2010 Dec;17(12):1461-9. doi: 10.1038/nsmb.1943. Epub 2010 Nov 14. Nat Struct Mol Biol. 2010. PMID: 21076401 Free PMC article.
61 results