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Alternative polyadenylation alters protein dosage by switching between intronic and 3'UTR sites.
de Prisco N, Ford C, Elrod ND, Lee W, Tang LC, Huang KL, Lin A, Ji P, Jonnakuti VS, Boyle L, Cabaj M, Botta S, Õunap K, Reinson K, Wojcik MH, Rosenfeld JA, Bi W, Tveten K, Prescott T, Gerstner T, Schroeder A, Fong CT, George-Abraham JK, Buchanan CA, Hanson-Khan A, Bernstein JA, Nella AA, Chung WK, Brandt V, Jovanovic M, Targoff KL, Yalamanchili HK, Wagner EJ, Gennarino VA. de Prisco N, et al. Among authors: targoff kl. Sci Adv. 2023 Feb 17;9(7):eade4814. doi: 10.1126/sciadv.ade4814. Epub 2023 Feb 17. Sci Adv. 2023. PMID: 36800428 Free PMC article.
Nkx genes are essential for maintenance of ventricular identity.
Targoff KL, Colombo S, George V, Schell T, Kim SH, Solnica-Krezel L, Yelon D. Targoff KL, et al. Development. 2013 Oct;140(20):4203-13. doi: 10.1242/dev.095562. Epub 2013 Sep 11. Development. 2013. PMID: 24026123 Free PMC article.
Photoactivatable Cre recombinase 3.0 for in vivo mouse applications.
Morikawa K, Furuhashi K, de Sena-Tomas C, Garcia-Garcia AL, Bekdash R, Klein AD, Gallerani N, Yamamoto HE, Park SE, Collins GS, Kawano F, Sato M, Lin CS, Targoff KL, Au E, Salling MC, Yazawa M. Morikawa K, et al. Among authors: targoff kl. Nat Commun. 2020 May 1;11(1):2141. doi: 10.1038/s41467-020-16030-0. Nat Commun. 2020. PMID: 32358538 Free PMC article.
UV microspot irradiator at Columbia University.
Bigelow AW, Ponnaiya B, Targoff KL, Brenner DJ. Bigelow AW, et al. Among authors: targoff kl. Radiat Environ Biophys. 2013 Aug;52(3):411-7. doi: 10.1007/s00411-013-0474-9. Epub 2013 May 26. Radiat Environ Biophys. 2013. PMID: 23708525 Free PMC article.
18 results