Tarasov AI - Search Results

1

Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.

Haythorne E, Lloyd M, Walsby-Tickle J, Tarasov AI, Sandbrink J, Portillo I, Exposito RT, Sachse G, Cyranka M, Rohm M, Rorsman P, McCullagh J, Ashcroft FM. Haythorne E, et al. Among authors: tarasov ai. Nat Commun. 2022 Nov 14;13(1):6754. doi: 10.1038/s41467-022-34095-x. Nat Commun. 2022. PMID: 36376280 Free PMC article.

2

Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.

Dabrowski M, Tarasov A, Ashcroft FM. Dabrowski M, et al. J Physiol. 2004 Jun 1;557(Pt 2):347-54. doi: 10.1113/jphysiol.2003.059105. Epub 2004 Mar 5. J Physiol. 2004. PMID: 15004210 Free PMC article.

3

Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux.

Tarasov A, Dusonchet J, Ashcroft F. Tarasov A, et al. Diabetes. 2004 Dec;53 Suppl 3:S113-22. doi: 10.2337/diabetes.53.suppl_3.s113. Diabetes. 2004. PMID: 15561898 Review.

4

ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells.

Tarasov AI, Girard CA, Ashcroft FM. Tarasov AI, et al. Diabetes. 2006 Sep;55(9):2446-54. doi: 10.2337/db06-0360. Diabetes. 2006. PMID: 16936192

5

A Kir6.2 mutation causing neonatal diabetes impairs electrical activity and insulin secretion from INS-1 beta-cells.

Tarasov AI, Welters HJ, Senkel S, Ryffel GU, Hattersley AT, Morgan NG, Ashcroft FM. Tarasov AI, et al. Diabetes. 2006 Nov;55(11):3075-82. doi: 10.2337/db06-0637. Diabetes. 2006. PMID: 17065345

6

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

Olofsson CS, Collins S, Bengtsson M, Eliasson L, Salehi A, Shimomura K, Tarasov A, Holm C, Ashcroft F, Rorsman P. Olofsson CS, et al. Diabetes. 2007 Jul;56(7):1888-97. doi: 10.2337/db06-1150. Epub 2007 Apr 24. Diabetes. 2007. PMID: 17456851 Free article.

7

Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.

Haider S, Tarasov AI, Craig TJ, Sansom MS, Ashcroft FM. Haider S, et al. Among authors: tarasov ai. EMBO J. 2007 Aug 22;26(16):3749-59. doi: 10.1038/sj.emboj.7601809. Epub 2007 Aug 2. EMBO J. 2007. PMID: 17673911 Free PMC article.

8

Functional analysis of two Kir6.2 (KCNJ11) mutations, K170T and E322K, causing neonatal diabetes.

Tarasov AI, Girard CA, Larkin B, Tammaro P, Flanagan SE, Ellard S, Ashcroft FM. Tarasov AI, et al. Diabetes Obes Metab. 2007 Nov;9 Suppl 2:46-55. doi: 10.1111/j.1463-1326.2007.00777.x. Diabetes Obes Metab. 2007. PMID: 17919178

9

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.

Zhang Q, Ramracheya R, Lahmann C, Tarasov A, Bengtsson M, Braha O, Braun M, Brereton M, Collins S, Galvanovskis J, Gonzalez A, Groschner LN, Rorsman NJ, Salehi A, Travers ME, Walker JN, Gloyn AL, Gribble F, Johnson PR, Reimann F, Ashcroft FM, Rorsman P. Zhang Q, et al. Cell Metab. 2013 Dec 3;18(6):871-82. doi: 10.1016/j.cmet.2013.10.014. Cell Metab. 2013. PMID: 24315372 Free PMC article.

10

Dramatis Personae in β-Cell Mass Regulation: Enter SerpinB1.

Tarasov AI, Rorsman P. Tarasov AI, et al. Cell Metab. 2016 Jan 12;23(1):8-10. doi: 10.1016/j.cmet.2015.12.011. Cell Metab. 2016. PMID: 26771113 Free article.

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