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A Mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-Guérin.
Woodworth JS, Clemmensen HS, Battey H, Dijkman K, Lindenstrøm T, Laureano RS, Taplitz R, Morgan J, Aagaard C, Rosenkrands I, Lindestam Arlehamn CS, Andersen P, Mortensen R. Woodworth JS, et al. Among authors: taplitz r. Nat Commun. 2021 Nov 18;12(1):6658. doi: 10.1038/s41467-021-26934-0. Nat Commun. 2021. PMID: 34795205 Free PMC article.
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A. Lindestam Arlehamn CS, et al. Among authors: taplitz r. PLoS Pathog. 2013 Jan;9(1):e1003130. doi: 10.1371/journal.ppat.1003130. Epub 2013 Jan 24. PLoS Pathog. 2013. PMID: 23358848 Free PMC article.
HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients.
Tippalagama R, Singhania A, Dubelko P, Lindestam Arlehamn CS, Crinklaw A, Pomaznoy M, Seumois G, deSilva AD, Premawansa S, Vidanagama D, Gunasena B, Goonawardhana NDS, Ariyaratne D, Scriba TJ, Gilman RH, Saito M, Taplitz R, Vijayanand P, Sette A, Peters B, Burel JG. Tippalagama R, et al. Among authors: taplitz r. J Immunol. 2021 Jul 15;207(2):523-533. doi: 10.4049/jimmunol.2100011. Epub 2021 Jun 30. J Immunol. 2021. PMID: 34193602 Free PMC article.
T-cell deficiency and hyperinflammatory monocyte responses associate with Mycobacterium avium complex lung disease.
Lindestam Arlehamn CS, Benson B, Kuan R, Dill-McFarland KA, Peterson GJ, Paul S, Nguyen FK, Gilman RH, Saito M, Taplitz R, Arentz M, Goss CH, Aitken ML, Horne DJ, Shah JA, Sette A, Hawn TR. Lindestam Arlehamn CS, et al. Among authors: taplitz r. Front Immunol. 2022 Oct 3;13:1016038. doi: 10.3389/fimmu.2022.1016038. eCollection 2022. Front Immunol. 2022. PMID: 36263044 Free PMC article.
An Integrated Workflow To Assess Technical and Biological Variability of Cell Population Frequencies in Human Peripheral Blood by Flow Cytometry.
Burel JG, Qian Y, Lindestam Arlehamn C, Weiskopf D, Zapardiel-Gonzalo J, Taplitz R, Gilman RH, Saito M, de Silva AD, Vijayanand P, Scheuermann RH, Sette A, Peters B. Burel JG, et al. Among authors: taplitz r. J Immunol. 2017 Feb 15;198(4):1748-1758. doi: 10.4049/jimmunol.1601750. Epub 2017 Jan 9. J Immunol. 2017. PMID: 28069807 Free PMC article.
Circulating T cell-monocyte complexes are markers of immune perturbations.
Burel JG, Pomaznoy M, Lindestam Arlehamn CS, Weiskopf D, da Silva Antunes R, Jung Y, Babor M, Schulten V, Seumois G, Greenbaum JA, Premawansa S, Premawansa G, Wijewickrama A, Vidanagama D, Gunasena B, Tippalagama R, deSilva AD, Gilman RH, Saito M, Taplitz R, Ley K, Vijayanand P, Sette A, Peters B. Burel JG, et al. Among authors: taplitz r. Elife. 2019 Jun 25;8:e46045. doi: 10.7554/eLife.46045. Elife. 2019. PMID: 31237234 Free PMC article.
Correction: Quantitative and Qualitative Perturbations of CD8+ MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals.
Pomaznoy M, Kuan R, Lindvall M, Burel JG, Seumois G, Vijayanand P, Taplitz R, Gilman RH, Saito M, Lewinsohn DM, Sette A, Peters B, Lindestam Arlehamn CS. Pomaznoy M, et al. Among authors: taplitz r. Immunohorizons. 2020 Jul 22;4(7):442-443. doi: 10.4049/immunohorizons.2000064. Immunohorizons. 2020. PMID: 32699177 Free PMC article. No abstract available.
Safety and immunogenicity of a synthetic multiantigen modified vaccinia virus Ankara-based COVID-19 vaccine (COH04S1): an open-label and randomised, phase 1 trial.
Chiuppesi F, Zaia JA, Frankel PH, Stan R, Drake J, Williams B, Acosta AM, Francis K, Taplitz RA, Dickter JK, Dadwal S, Puing AG, Nanayakkara DD, Ash P, Cui Y, Contreras H, La Rosa C, Tiemann K, Park Y, Medina J, Iniguez A, Zhou Q, Karpinski V, Johnson D, Faircloth K, Kaltcheva T, Nguyen J, Kha M, Nguyen VH, Francisco SO, Grifoni A, Wong A, Sette A, Wussow F, Diamond DJ. Chiuppesi F, et al. Among authors: taplitz ra. Lancet Microbe. 2022 Apr;3(4):e252-e264. doi: 10.1016/S2666-5247(22)00027-1. Epub 2022 Mar 9. Lancet Microbe. 2022. PMID: 35287430 Free PMC article. Clinical Trial.
68 results