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Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Tapias V, Jainuddin S, Ahuja M, Stack C, Elipenahli C, Vignisse J, Gerges M, Starkova N, Xu H, Starkov AA, Bettendorff L, Hushpulian DM, Smirnova NA, Gazaryan IG, Kaidery NA, Wakade S, Calingasan NY, Thomas B, Gibson GE, Dumont M, Beal MF. Tapias V, et al. Hum Mol Genet. 2018 Aug 15;27(16):2874-2892. doi: 10.1093/hmg/ddy201. Hum Mol Genet. 2018. PMID: 29860433 Free PMC article.
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
Yang Y, Tapias V, Acosta D, Xu H, Chen H, Bhawal R, Anderson ET, Ivanova E, Lin H, Sagdullaev BT, Chen J, Klein WL, Viola KL, Gandy S, Haroutunian V, Beal MF, Eliezer D, Zhang S, Gibson GE. Yang Y, et al. Among authors: tapias v. Nat Commun. 2022 Jan 10;13(1):159. doi: 10.1038/s41467-021-27572-2. Nat Commun. 2022. PMID: 35013160 Free PMC article.
A highly reproducible rotenone model of Parkinson's disease.
Cannon JR, Tapias V, Na HM, Honick AS, Drolet RE, Greenamyre JT. Cannon JR, et al. Among authors: tapias v. Neurobiol Dis. 2009 May;34(2):279-90. doi: 10.1016/j.nbd.2009.01.016. Neurobiol Dis. 2009. PMID: 19385059 Free PMC article.
41 results