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An exercise-inducible metabolite that suppresses feeding and obesity.
Li VL, He Y, Contrepois K, Liu H, Kim JT, Wiggenhorn AL, Tanzo JT, Tung AS, Lyu X, Zushin PH, Jansen RS, Michael B, Loh KY, Yang AC, Carl CS, Voldstedlund CT, Wei W, Terrell SM, Moeller BC, Arthur RM, Wallis GA, van de Wetering K, Stahl A, Kiens B, Richter EA, Banik SM, Snyder MP, Xu Y, Long JZ. Li VL, et al. Among authors: tanzo jt. Nature. 2022 Jun;606(7915):785-790. doi: 10.1038/s41586-022-04828-5. Epub 2022 Jun 15. Nature. 2022. PMID: 35705806 Free PMC article.
Targeted glycan degradation potentiates the anticancer immune response in vivo.
Gray MA, Stanczak MA, Mantuano NR, Xiao H, Pijnenborg JFA, Malaker SA, Miller CL, Weidenbacher PA, Tanzo JT, Ahn G, Woods EC, Läubli H, Bertozzi CR. Gray MA, et al. Among authors: tanzo jt. Nat Chem Biol. 2020 Dec;16(12):1376-1384. doi: 10.1038/s41589-020-0622-x. Epub 2020 Aug 17. Nat Chem Biol. 2020. PMID: 32807964 Free PMC article.
Binding and sequestration of poison frog alkaloids by a plasma globulin.
Alvarez-Buylla A, Fischer MT, Moya Garzon MD, Rangel AE, Tapia EE, Tanzo JT, Soh HT, Coloma LA, Long JZ, O'Connell LA. Alvarez-Buylla A, et al. Among authors: tanzo jt. Elife. 2023 Dec 19;12:e85096. doi: 10.7554/eLife.85096. Elife. 2023. PMID: 38206862 Free PMC article.
CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.
Tanzo JT, Li VL, Wiggenhorn AL, Moya-Garzon MD, Wei W, Lyu X, Dong W, Tahir UA, Chen ZZ, Cruz DE, Deng S, Shi X, Zheng S, Guo Y, Sims M, Abu-Remaileh M, Wilson JG, Gerszten RE, Long JZ, Benson MD. Tanzo JT, et al. J Biol Chem. 2023 Jun;299(6):104764. doi: 10.1016/j.jbc.2023.104764. Epub 2023 Apr 28. J Biol Chem. 2023. PMID: 37121548 Free PMC article.
CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.
Tanzo JT, Li VL, Wiggenhorn AL, Moya-Garzon MD, Wei W, Lyu X, Dong W, Tahir UA, Chen ZZ, Cruz DE, Deng S, Shi X, Zheng S, Guo Y, Sims M, Abu-Remaileh M, Wilson JG, Gerszten RE, Long JZ, Benson MD. Tanzo JT, et al. bioRxiv [Preprint]. 2023 Mar 9:2023.03.09.531581. doi: 10.1101/2023.03.09.531581. bioRxiv. 2023. PMID: 36945562 Free PMC article. Updated. Preprint.