Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

44 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Essential structure of orexin 1 receptor antagonist YNT-707: Conversion of the 16-cyclopropylmethyl group to the 16-sulfonamide group in d-nor-nalfurafine derivatives.
Katoh K, Kutsumura N, Yamamoto N, Nagumo Y, Saitoh T, Ishikawa Y, Irukayama-Tomobe Y, Tanimura R, Yanagisawa M, Nagase H. Katoh K, et al. Among authors: tanimura r. Bioorg Med Chem Lett. 2022 Mar 1;59:128550. doi: 10.1016/j.bmcl.2022.128550. Epub 2022 Jan 15. Bioorg Med Chem Lett. 2022. PMID: 35041942
Discovery of Peripheral κ-Opioid Receptor Agonists as Novel Analgesics.
Suzuki S, Sugawara Y, Inada H, Tsuji R, Inoue A, Tanimura R, Shimozono R, Konno M, Ohyama T, Higashi E, Sakai C, Kawai K. Suzuki S, et al. Among authors: tanimura r. Chem Pharm Bull (Tokyo). 2017;65(11):1085-1088. doi: 10.1248/cpb.c17-00555. Chem Pharm Bull (Tokyo). 2017. PMID: 29093296 Free article.
Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity.
Saitoh T, Seki K, Nakajima R, Yamamoto N, Kutsumura N, Nagumo Y, Irukayama-Tomobe Y, Ogawa Y, Ishikawa Y, Tanimura R, Yanagisawa M, Nagase H. Saitoh T, et al. Among authors: tanimura r. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2655-2658. doi: 10.1016/j.bmcl.2019.07.039. Epub 2019 Jul 24. Bioorg Med Chem Lett. 2019. PMID: 31375290
Discovery of attenuation effect of orexin 1 receptor to aversion of nalfurafine: Synthesis and evaluation of D-nor-nalfurafine derivatives and analyses of the three active conformations of nalfurafine.
Nagumo Y, Katoh K, Iio K, Saitoh T, Kutsumura N, Yamamoto N, Ishikawa Y, Irukayama-Tomobe Y, Ogawa Y, Baba T, Tanimura R, Yanagisawa M, Nagase H. Nagumo Y, et al. Among authors: tanimura r. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127360. doi: 10.1016/j.bmcl.2020.127360. Epub 2020 Jun 19. Bioorg Med Chem Lett. 2020. PMID: 32738987
Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring.
Iio K, Saitoh T, Ohshita R, Hino T, Amezawa M, Takayama Y, Nagumo Y, Yamamoto N, Kutsumura N, Irukayama-Tomobe Y, Ishikawa Y, Tanimura R, Yanagisawa M, Nagase H. Iio K, et al. Among authors: tanimura r. Bioorg Med Chem Lett. 2022 Mar 15;60:128555. doi: 10.1016/j.bmcl.2022.128555. Epub 2022 Jan 17. Bioorg Med Chem Lett. 2022. PMID: 35051577
Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) library.
Saitoh T, Amezawa M, Horiuchi J, Nagumo Y, Yamamoto N, Kutsumura N, Ohshita R, Tokuda A, Irukayama-Tomobe Y, Ogawa Y, Ishikawa Y, Hasegawa E, Sakurai T, Uchida Y, Sato T, Gouda H, Tanimura R, Yanagisawa M, Nagase H. Saitoh T, et al. Among authors: tanimura r. Eur J Med Chem. 2022 Oct 5;240:114505. doi: 10.1016/j.ejmech.2022.114505. Epub 2022 Jun 13. Eur J Med Chem. 2022. PMID: 35839689
44 results