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Page 1
Discovery of new orally active prostaglandin D2 receptor antagonists.
Iwahashi M, Naganawa A, Kinoshita A, Shimabukuro A, Nishiyama T, Ogawa S, Matsunaga Y, Tsukamoto K, Okada Y, Matsumoto R, Nambu F, Oumi R, Odagaki Y, Katagi J, Yano K, Tani K, Nakai H, Toda M. Iwahashi M, et al. Among authors: tani k. Bioorg Med Chem. 2011 Nov 15;19(22):6935-48. doi: 10.1016/j.bmc.2011.08.065. Epub 2011 Sep 2. Bioorg Med Chem. 2011. PMID: 21982795
A practical synthesis and biological evaluation of 9-halogenated PGF analogues.
Tani K, Naganawa A, Ishida A, Egashira H, Odagaki Y, Miyazaki T, Hasegawa T, Kawanaka Y, Sagawa K, Harada H, Ogawa M, Maruyama T, Nakai H, Ohuchida S, Kondo K, Toda M. Tani K, et al. Bioorg Med Chem. 2002 Jun;10(6):1883-94. doi: 10.1016/s0968-0896(02)00008-1. Bioorg Med Chem. 2002. PMID: 11937346
Discovery of G Protein-Biased EP2 Receptor Agonists.
Ogawa S, Watanabe T, Sugimoto I, Moriyuki K, Goto Y, Yamane S, Watanabe A, Tsuboi K, Kinoshita A, Kigoshi H, Tani K, Maruyama T. Ogawa S, et al. Among authors: tani k. ACS Med Chem Lett. 2016 Jan 4;7(3):306-11. doi: 10.1021/acsmedchemlett.5b00455. eCollection 2016 Mar 10. ACS Med Chem Lett. 2016. PMID: 26985320 Free PMC article.
Discovery of Novel Seven-Membered Prostacyclin Analogues as Potent and Selective Prostaglandin FP and EP3 Dual Agonists.
Sugimoto I, Kambe T, Okino T, Obitsu T, Ohta N, Nishiyama T, Kinoshita A, Fujimoto T, Egashira H, Yamane S, Shuto S, Tani K, Maruyama T. Sugimoto I, et al. Among authors: tani k. ACS Med Chem Lett. 2016 Dec 13;8(1):107-112. doi: 10.1021/acsmedchemlett.6b00415. eCollection 2017 Jan 12. ACS Med Chem Lett. 2016. PMID: 28105284 Free PMC article.
Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.
Mutoh M, Watanabe K, Kitamura T, Shoji Y, Takahashi M, Kawamori T, Tani K, Kobayashi M, Maruyama T, Kobayashi K, Ohuchida S, Sugimoto Y, Narumiya S, Sugimura T, Wakabayashi K. Mutoh M, et al. Among authors: tani k. Cancer Res. 2002 Jan 1;62(1):28-32. Cancer Res. 2002. PMID: 11782353
1,211 results