Tang Y - Search Results

1

Multi-omics analysis identifies osteosarcoma subtypes with distinct prognosis indicating stratified treatment.

Jiang Y, Wang J, Sun M, Zuo D, Wang H, Shen J, Jiang W, Mu H, Ma X, Yin F, Lin J, Wang C, Yu S, Jiang L, Lv G, Liu F, Xue L, Tian K, Wang G, Zhou Z, Lv Y, Wang Z, Zhang T, Xu J, Yang L, Zhao K, Sun W, Tang Y, Cai Z, Wang S, Hua Y. Jiang Y, et al. Among authors: tang y. Nat Commun. 2022 Nov 23;13(1):7207. doi: 10.1038/s41467-022-34689-5. Nat Commun. 2022. PMID: 36418292 Free PMC article.

2

CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists.

Liu F, Jiang W, Sui Y, Meng W, Hou L, Li T, Li M, Zhang L, Mo J, Wang J, Zhao Y, Zhang L, Ma J, Tang Y. Liu F, et al. Among authors: tang y. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12986-12995. doi: 10.1073/pnas.1815780116. Epub 2019 Jun 10. Proc Natl Acad Sci U S A. 2019. PMID: 31182587 Free PMC article.

3

Inhibition of the FACT Complex Targets Aberrant Hedgehog Signaling and Overcomes Resistance to Smoothened Antagonists.

Mo J, Liu F, Sun X, Huang H, Tan K, Zhao X, Li R, Jiang W, Sui Y, Chen X, Shen K, Zhang L, Ma J, Zhao K, Tang Y. Mo J, et al. Among authors: tang y. Cancer Res. 2021 Jun 1;81(11):3105-3120. doi: 10.1158/0008-5472.CAN-20-3186. Epub 2021 Apr 14. Cancer Res. 2021. PMID: 33853831

4

Dissecting super-enhancer driven transcriptional dependencies reveals novel therapeutic strategies and targets for group 3 subtype medulloblastoma.

Li M, Han Y, Wang C, Kang W, Jiang W, Zhang L, Tang Y. Li M, et al. Among authors: tang y. J Exp Clin Cancer Res. 2022 Oct 22;41(1):311. doi: 10.1186/s13046-022-02506-y. J Exp Clin Cancer Res. 2022. PMID: 36273157 Free PMC article.

5

Therapeutic targeting the oncogenic driver EWSR1::FLI1 in Ewing sarcoma through inhibition of the FACT complex.

Mo J, Tan K, Dong Y, Lu W, Liu F, Mei Y, Huang H, Zhao K, Lv Z, Ye Y, Tang Y. Mo J, et al. Among authors: tang y. Oncogene. 2023 Jan;42(1):11-25. doi: 10.1038/s41388-022-02533-1. Epub 2022 Nov 10. Oncogene. 2023. PMID: 36357572

6

Effective inhibition of MYC-amplified group 3 medulloblastoma by FACT-targeted curaxin drug CBL0137.

Wang J, Sui Y, Li Q, Zhao Y, Dong X, Yang J, Liang Z, Han Y, Tang Y, Ma J. Wang J, et al. Among authors: tang y. Cell Death Dis. 2020 Dec 2;11(12):1029. doi: 10.1038/s41419-020-03201-6. Cell Death Dis. 2020. PMID: 33268769 Free PMC article.

7

Context-dependent tumor-suppressive BMP signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of CXXC5.

Sun Y, Yan K, Wang Y, Xu C, Wang D, Zhou W, Guo S, Han Y, Tang L, Shao Y, Shan S, Zhang QC, Tang Y, Zhang L, Xi Q. Sun Y, et al. Among authors: tang y, tang l. Nat Cancer. 2022 Sep;3(9):1105-1122. doi: 10.1038/s43018-022-00408-8. Epub 2022 Aug 1. Nat Cancer. 2022. PMID: 35915262

8

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Grasso CS, et al. Among authors: tang y. Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4. Nat Med. 2015. PMID: 25939062 Free PMC article.

9

THZ1 reveals CDK7-dependent transcriptional addictions in pancreatic cancer.

Lu P, Geng J, Zhang L, Wang Y, Niu N, Fang Y, Liu F, Shi J, Zhang ZG, Sun YW, Wang LW, Tang Y, Xue J. Lu P, et al. Among authors: tang y. Oncogene. 2019 May;38(20):3932-3945. doi: 10.1038/s41388-019-0701-1. Epub 2019 Jan 28. Oncogene. 2019. PMID: 30692639

10

Single-cell transcriptomics uncovers cellular architecture and developmental trajectories in hepatoblastoma.

Huang H, Wu L, Lu L, Zhang Z, Qiu B, Mo J, Luo Y, Xi Z, Feng M, Wan P, Zhu J, Yu D, Wu W, Tan K, Liu J, Sheng Q, Xu T, Huang J, Lv Z, Tang Y, Xia Q. Huang H, et al. Among authors: tang y. Hepatology. 2023 Jun 1;77(6):1911-1928. doi: 10.1002/hep.32775. Epub 2023 Mar 29. Hepatology. 2023. PMID: 36059151

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