Tang EK - Search Results

1

Design, synthesis, and biological action of 20R-hydroxyvitamin D3.

Lu Y, Chen J, Janjetovic Z, Michaels P, Tang EK, Wang J, Tuckey RC, Slominski AT, Li W, Miller DD. Lu Y, et al. Among authors: tang ek. J Med Chem. 2012 Apr 12;55(7):3573-7. doi: 10.1021/jm201478e. Epub 2012 Mar 20. J Med Chem. 2012. PMID: 22404326 Free PMC article.

2

20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.

Slominski AT, Kim TK, Janjetovic Z, Tuckey RC, Bieniek R, Yue J, Li W, Chen J, Nguyen MN, Tang EK, Miller D, Chen TC, Holick M. Slominski AT, et al. Among authors: tang ek. Am J Physiol Cell Physiol. 2011 Mar;300(3):C526-41. doi: 10.1152/ajpcell.00203.2010. Epub 2010 Dec 15. Am J Physiol Cell Physiol. 2011. PMID: 21160030 Free PMC article.

3

In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1.

Slominski AT, Kim TK, Shehabi HZ, Semak I, Tang EK, Nguyen MN, Benson HA, Korik E, Janjetovic Z, Chen J, Yates CR, Postlethwaite A, Li W, Tuckey RC. Slominski AT, et al. Among authors: tang ek. FASEB J. 2012 Sep;26(9):3901-15. doi: 10.1096/fj.12-208975. Epub 2012 Jun 8. FASEB J. 2012. PMID: 22683847 Free PMC article.

4

Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity.

Chen J, Wang J, Kim TK, Tieu EW, Tang EK, Lin Z, Kovacic D, Miller DD, Postlethwaite A, Tuckey RC, Slominski AT, Li W. Chen J, et al. Among authors: tang ek. Anticancer Res. 2014 May;34(5):2153-63. Anticancer Res. 2014. PMID: 24778017 Free PMC article.

5

1α,20S-Dihydroxyvitamin D₃ Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis.

Lin Z, Chen H, Belorusova AY, Bollinger JC, Tang EKY, Janjetovic Z, Kim TK, Wu Z, Miller DD, Slominski AT, Postlethwaite AE, Tuckey RC, Rochel N, Li W. Lin Z, et al. Sci Rep. 2017 Aug 31;7(1):10193. doi: 10.1038/s41598-017-10917-7. Sci Rep. 2017. PMID: 28860545 Free PMC article.

6

Metabolism of substrates incorporated into phospholipid vesicles by mouse 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1).

Tang EK, Voo KJ, Nguyen MN, Tuckey RC. Tang EK, et al. J Steroid Biochem Mol Biol. 2010 Apr;119(3-5):171-9. doi: 10.1016/j.jsbmb.2010.02.022. Epub 2010 Mar 1. J Steroid Biochem Mol Biol. 2010. PMID: 20193763

7

Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activity.

Tang EK, Li W, Janjetovic Z, Nguyen MN, Wang Z, Slominski A, Tuckey RC. Tang EK, et al. Drug Metab Dispos. 2010 Sep;38(9):1553-9. doi: 10.1124/dmd.110.034389. Epub 2010 Jun 16. Drug Metab Dispos. 2010. PMID: 20554701 Free PMC article.

8

Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength.

Kim TK, Wang J, Janjetovic Z, Chen J, Tuckey RC, Nguyen MN, Tang EK, Miller D, Li W, Slominski AT. Kim TK, et al. Among authors: tang ek. Mol Cell Endocrinol. 2012 Sep 25;361(1-2):143-52. doi: 10.1016/j.mce.2012.04.001. Epub 2012 Apr 21. Mol Cell Endocrinol. 2012. PMID: 22546549 Free PMC article.

9

Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.

Tang EK, Chen J, Janjetovic Z, Tieu EW, Slominski AT, Li W, Tuckey RC. Tang EK, et al. Drug Metab Dispos. 2013 May;41(5):1112-24. doi: 10.1124/dmd.113.050955. Epub 2013 Mar 1. Drug Metab Dispos. 2013. PMID: 23454830 Free PMC article.

10

In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.

Slominski AT, Kim TK, Shehabi HZ, Tang EK, Benson HA, Semak I, Lin Z, Yates CR, Wang J, Li W, Tuckey RC. Slominski AT, et al. Among authors: tang ek. Mol Cell Endocrinol. 2014 Mar 5;383(1-2):181-92. doi: 10.1016/j.mce.2013.12.012. Epub 2013 Dec 29. Mol Cell Endocrinol. 2014. PMID: 24382416 Free PMC article.

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