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Polythiol-containing, recombinant mannosylated-albumin is a superior CD68+/CD206+ Kupffer cell-targeted nanoantioxidant for treatment of two acute hepatitis models.
Maeda H, Hirata K, Watanabe H, Ishima Y, Chuang VT, Taguchi K, Inatsu A, Kinoshita M, Tanaka M, Sasaki Y, Otagiri M, Maruyama T. Maeda H, et al. Among authors: tanaka m. J Pharmacol Exp Ther. 2015 Feb;352(2):244-57. doi: 10.1124/jpet.114.219493. Epub 2014 Nov 14. J Pharmacol Exp Ther. 2015. PMID: 25398242
Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions.
Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T. Minayoshi Y, et al. Among authors: tanaka m. Drug Deliv. 2018 Nov;25(1):1067-1077. doi: 10.1080/10717544.2018.1464083. Drug Deliv. 2018. PMID: 29688069 Free PMC article.
Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH.
Maeda H, Ishima Y, Saruwatari J, Mizuta Y, Minayoshi Y, Ichimizu S, Yanagisawa H, Nagasaki T, Yasuda K, Oshiro S, Taura M, McConnell MJ, Oniki K, Sonoda K, Wakayama T, Kinoshita M, Shuto T, Kai H, Tanaka M, Sasaki Y, Iwakiri Y, Otagiri M, Watanabe H, Maruyama T. Maeda H, et al. Among authors: tanaka m. J Control Release. 2022 Jan;341:457-474. doi: 10.1016/j.jconrel.2021.11.039. Epub 2021 Nov 29. J Control Release. 2022. PMID: 34856227
Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases.
Nagumo K, Tanaka M, Chuang VT, Setoyama H, Watanabe H, Yamada N, Kubota K, Tanaka M, Matsushita K, Yoshida A, Jinnouchi H, Anraku M, Kadowaki D, Ishima Y, Sasaki Y, Otagiri M, Maruyama T. Nagumo K, et al. Among authors: tanaka m. PLoS One. 2014 Jan 8;9(1):e85216. doi: 10.1371/journal.pone.0085216. eCollection 2014. PLoS One. 2014. PMID: 24416365 Free PMC article.
[Diagnosis of portal hypertension].
Naoe H, Tanaka M, Sasaki Y. Naoe H, et al. Among authors: tanaka m. Nihon Shokakibyo Gakkai Zasshi. 2019;116(5):374-385. doi: 10.11405/nisshoshi.116.374. Nihon Shokakibyo Gakkai Zasshi. 2019. PMID: 31080217 Japanese. No abstract available.
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