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Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.
Tolani B, Celli A, Yao Y, Tan YZ, Fetter R, Liem CR, de Smith AJ, Vasanthakumar T, Bisignano P, Cotton AD, Seiple IB, Rubinstein JL, Jost M, Weissman JS. Tolani B, et al. Among authors: tan yz. Nat Biotechnol. 2022 Dec;40(12):1834-1844. doi: 10.1038/s41587-022-01386-z. Epub 2022 Jul 25. Nat Biotechnol. 2022. PMID: 35879364 Free PMC article.
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP. Rujas E, et al. Among authors: tan yz. Nat Commun. 2021 Jun 16;12(1):3661. doi: 10.1038/s41467-021-23825-2. Nat Commun. 2021. PMID: 34135340 Free PMC article.
Structure of V-ATPase from citrus fruit.
Tan YZ, Keon KA, Abdelaziz R, Imming P, Schulze W, Schumacher K, Rubinstein JL. Tan YZ, et al. Structure. 2022 Oct 6;30(10):1403-1410.e4. doi: 10.1016/j.str.2022.07.006. Epub 2022 Aug 29. Structure. 2022. PMID: 36041457 Free article.
FACT caught in the act of manipulating the nucleosome.
Liu Y, Zhou K, Zhang N, Wei H, Tan YZ, Zhang Z, Carragher B, Potter CS, D'Arcy S, Luger K. Liu Y, et al. Among authors: tan yz. Nature. 2020 Jan;577(7790):426-431. doi: 10.1038/s41586-019-1820-0. Epub 2019 Nov 27. Nature. 2020. PMID: 31775157 Free PMC article.
Overcoming resolution attenuation during tilted cryo-EM data collection.
Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, McKenna R, Agbandje-McKenna M, Benner SA, Noel JAP, Wang D, Tan YZ, Lyumkis D. Aiyer S, et al. Among authors: tan sm, tan yz. Nat Commun. 2024 Jan 9;15(1):389. doi: 10.1038/s41467-023-44555-7. Nat Commun. 2024. PMID: 38195598 Free PMC article.
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Kim J, Tan YZ, Wicht KJ, Erramilli SK, Dhingra SK, Okombo J, Vendome J, Hagenah LM, Giacometti SI, Warren AL, Nosol K, Roepe PD, Potter CS, Carragher B, Kossiakoff AA, Quick M, Fidock DA, Mancia F. Kim J, et al. Among authors: tan yz. Nature. 2019 Dec;576(7786):315-320. doi: 10.1038/s41586-019-1795-x. Epub 2019 Nov 27. Nature. 2019. PMID: 31776516 Free PMC article.
266 results