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Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists.
J Med Chem. 2006 Oct 19;49(21):6421-4. doi: 10.1021/jm060663c.
J Med Chem. 2006.
PMID: 17034149
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system.
Hwang DR, Wu YS, Chang CW, Lien TW, Chen WC, Tan UK, Hsu JT, Hsieh HP.
Hwang DR, et al. Among authors: tan uk.
Bioorg Med Chem. 2006 Jan 1;14(1):83-91. doi: 10.1016/j.bmc.2005.07.055. Epub 2005 Sep 2.
Bioorg Med Chem. 2006.
PMID: 16140536
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Aurora kinase A inhibitors: identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold.
Coumar MS, Wu JS, Leou JS, Tan UK, Chang CY, Chang TY, Lin WH, Hsu JT, Chao YS, Wu SY, Hsieh HP.
Coumar MS, et al. Among authors: tan uk.
Bioorg Med Chem Lett. 2008 Mar 1;18(5):1623-7. doi: 10.1016/j.bmcl.2008.01.068. Epub 2008 Jan 19.
Bioorg Med Chem Lett. 2008.
PMID: 18243698
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Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
Reddy GR, Kuo CC, Tan UK, Coumar MS, Chang CY, Chiang YK, Lai MJ, Yeh JY, Wu SY, Chang JY, Liou JP, Hsieh HP.
Reddy GR, et al. Among authors: tan uk.
J Med Chem. 2008 Dec 25;51(24):8163-7. doi: 10.1021/jm8008635.
J Med Chem. 2008.
PMID: 19053773
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Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity.
Coumar MS, Leou JS, Shukla P, Wu JS, Dixit AK, Lin WH, Chang CY, Lien TW, Tan UK, Chen CH, Hsu JT, Chao YS, Wu SY, Hsieh HP.
Coumar MS, et al. Among authors: tan uk.
J Med Chem. 2009 Feb 26;52(4):1050-62. doi: 10.1021/jm801270e.
J Med Chem. 2009.
PMID: 19140666
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Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents.
Hsieh HP, Liou JP, Lin YT, Mahindroo N, Chang JY, Yang YN, Chern SS, Tan UK, Chang CW, Chen TW, Lin CH, Chang YY, Wang CC.
Hsieh HP, et al. Among authors: tan uk.
Bioorg Med Chem Lett. 2003 Jan 6;13(1):101-5. doi: 10.1016/s0960-894x(02)00850-8.
Bioorg Med Chem Lett. 2003.
PMID: 12467626
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Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents.
Liou JP, Mahindroo N, Chang CW, Guo FM, Lee SW, Tan UK, Yeh TK, Kuo CC, Chang YW, Lu PH, Tung YS, Lin KT, Chang JY, Hsieh HP.
Liou JP, et al. Among authors: tan uk.
ChemMedChem. 2006 Oct;1(10):1106-18. doi: 10.1002/cmdc.200600125.
ChemMedChem. 2006.
PMID: 16952120
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Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach.
Wu YS, Coumar MS, Chang JY, Sun HY, Kuo FM, Kuo CC, Chen YJ, Chang CY, Hsiao CL, Liou JP, Chen CP, Yao HT, Chiang YK, Tan UK, Chen CT, Chu CY, Wu SY, Yeh TK, Lin CY, Hsieh HP.
Wu YS, et al. Among authors: tan uk.
J Med Chem. 2009 Aug 13;52(15):4941-5. doi: 10.1021/jm900060s.
J Med Chem. 2009.
PMID: 19586033
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