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Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma.
Gleason CE, Dickson MA, Klein Dooley ME, Antonescu CR, Gularte-Mérida R, Benitez M, Delgado JI, Kataru RP, Tan MWY, Bradic M, Adamson TE, Seier K, Richards AL, Palafox M, Chan E, D'Angelo SP, Gounder MM, Keohan ML, Kelly CM, Chi P, Movva S, Landa J, Crago AM, Donoghue MTA, Qin LX, Serra V, Turkekul M, Barlas A, Firester DM, Manova-Todorova K, Mehrara BJ, Kovatcheva M, Tan NS, Singer S, Tap WD, Koff A. Gleason CE, et al. Among authors: tan mwy. Clin Cancer Res. 2024 Feb 16;30(4):703-718. doi: 10.1158/1078-0432.CCR-23-2378. Clin Cancer Res. 2024. PMID: 37695642 Free PMC article.
Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice.
Tan MWY, Sng MK, Cheng HS, Low ZS, Leong BJJ, Chua D, Tan EHP, Chan JSK, Yip YS, Lee YH, Pal M, Wang X, Wahli W, Tan NS. Tan MWY, et al. Cell Death Differ. 2020 Sep;27(9):2668-2680. doi: 10.1038/s41418-020-0535-y. Epub 2020 Apr 20. Cell Death Differ. 2020. PMID: 32313198 Free PMC article.