Tan DS - Search Results

1

Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics.

Leus IV, Adamiak J, Chandar B, Bonifay V, Zhao S, Walker SS, Squadroni B, Balibar CJ, Kinarivala N, Standke LC, Voss HU, Tan DS, Rybenkov VV, Zgurskaya HI. Leus IV, et al. Among authors: tan ds. Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0137722. doi: 10.1128/aac.01377-22. Epub 2023 Jan 30. Antimicrob Agents Chemother. 2023. PMID: 36715507 Free PMC article.

2

Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents.

Bythrow GV, Mohandas P, Guney T, Standke LC, Germain GA, Lu X, Ji C, Levendosky K, Chavadi SS, Tan DS, Quadri LEN. Bythrow GV, et al. Among authors: tan ds. Biochemistry. 2019 Feb 12;58(6):833-847. doi: 10.1021/acs.biochem.8b01153. Epub 2019 Jan 10. Biochemistry. 2019. PMID: 30582694 Free PMC article.

3

Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors.

Lux MC, Standke LC, Tan DS. Lux MC, et al. Among authors: tan ds. J Antibiot (Tokyo). 2019 Jun;72(6):325-349. doi: 10.1038/s41429-019-0171-2. Epub 2019 Apr 15. J Antibiot (Tokyo). 2019. PMID: 30982830 Free PMC article. Review.

4

Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes.

Kinarivala N, Standke LC, Guney T, Ji C, Noguchi N, Asano Y, Tan DS. Kinarivala N, et al. Among authors: tan ds. Methods Enzymol. 2020;638:69-87. doi: 10.1016/bs.mie.2020.04.051. Epub 2020 May 5. Methods Enzymol. 2020. PMID: 32416922 Free PMC article.

5

Defining new chemical space for drug penetration into Gram-negative bacteria.

Zhao S, Adamiak JW, Bonifay V, Mehla J, Zgurskaya HI, Tan DS. Zhao S, et al. Among authors: tan ds. Nat Chem Biol. 2020 Dec;16(12):1293-1302. doi: 10.1038/s41589-020-00674-6. Epub 2020 Nov 16. Nat Chem Biol. 2020. PMID: 33199906 Free PMC article. Review.

6

Engineering CAR-T cells to activate small-molecule drugs in situ.

Gardner TJ, Lee JP, Bourne CM, Wijewarnasuriya D, Kinarivala N, Kurtz KG, Corless BC, Dacek MM, Chang AY, Mo G, Nguyen KM, Brentjens RJ, Tan DS, Scheinberg DA. Gardner TJ, et al. Among authors: tan ds. Nat Chem Biol. 2022 Feb;18(2):216-225. doi: 10.1038/s41589-021-00932-1. Epub 2021 Dec 30. Nat Chem Biol. 2022. PMID: 34969970 Free PMC article.

7

Design and synthesis of a library of C2-substituted sulfamidoadenosines to probe bacterial permeability.

Zhao S, Maceren J, Chung M, Stone S, Geißen R, Boby ML, Sherborne BS, Tan DS. Zhao S, et al. Among authors: tan ds. Bioorg Med Chem Lett. 2024 Jan 1;97:129486. doi: 10.1016/j.bmcl.2023.129486. Epub 2023 Sep 20. Bioorg Med Chem Lett. 2024. PMID: 37734424

8

General platform for systematic quantitative evaluation of small-molecule permeability in bacteria.

Davis TD, Gerry CJ, Tan DS. Davis TD, et al. Among authors: tan ds. ACS Chem Biol. 2014 Nov 21;9(11):2535-44. doi: 10.1021/cb5003015. Epub 2014 Sep 8. ACS Chem Biol. 2014. PMID: 25198656 Free PMC article.

9

Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa.

Ji C, Sharma I, Pratihar D, Hudson LL, Maura D, Guney T, Rahme LG, Pesci EC, Coleman JP, Tan DS. Ji C, et al. Among authors: tan ds. ACS Chem Biol. 2016 Nov 18;11(11):3061-3067. doi: 10.1021/acschembio.6b00575. Epub 2016 Sep 22. ACS Chem Biol. 2016. PMID: 27658001 Free PMC article.

10

Host Interactions with Engineered T-cell Micropharmacies.

Bourne CM, Wallisch P, Dacek MM, Gardner TJ, Pierre S, Vogt K, Corless BC, Bah MA, Romero-Pichardo JE, Charles A, Kurtz KG, Tan DS, Scheinberg DA. Bourne CM, et al. Among authors: tan ds. Cancer Immunol Res. 2023 Sep 1;11(9):1253-1265. doi: 10.1158/2326-6066.CIR-22-0879. Cancer Immunol Res. 2023. PMID: 37379366 Free PMC article.

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