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Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.
Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK. Rogers JL, et al. Among authors: tambar uk. J Med Chem. 2013 Feb 28;56(4):1739-47. doi: 10.1021/jm301847z. Epub 2013 Feb 18. J Med Chem. 2013. PMID: 23363003 Free PMC article.
Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2.
Scheuermann TH, Stroud D, Sleet CE, Bayeh L, Shokri C, Wang H, Caldwell CG, Longgood J, MacMillan JB, Bruick RK, Gardner KH, Tambar UK. Scheuermann TH, et al. Among authors: tambar uk. J Med Chem. 2015 Aug 13;58(15):5930-41. doi: 10.1021/acs.jmedchem.5b00529. Epub 2015 Jul 30. J Med Chem. 2015. PMID: 26226049
Total Synthesis of (+)-Rubellin C.
Gartman JA, Tambar UK. Gartman JA, et al. Among authors: tambar uk. Org Lett. 2020 Dec 4;22(23):9145-9150. doi: 10.1021/acs.orglett.0c02127. Epub 2020 Jul 30. Org Lett. 2020. PMID: 32806220 Free PMC article.
Synthesis of Cell-Permeable N-Acetylhexosamine 1-Phosphates.
Kakde BN, Capota E, Kohler JJ, Tambar UK. Kakde BN, et al. Among authors: tambar uk. J Org Chem. 2021 Dec 17;86(24):18257-18264. doi: 10.1021/acs.joc.1c01781. Epub 2021 Oct 7. J Org Chem. 2021. PMID: 34618463 Free PMC article.
52 results