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Page 1
Innovative tools and methods for toxicity testing within PARC work package 5 on hazard assessment.
De Castelbajac T, Aiello K, Arenas CG, Svingen T, Ramhøj L, Zalko D, Barouki R, Vanhaecke T, Rogiers V, Audebert M, Oelgeschlaeger M, Braeuning A, Blanc E, Tal T, Rüegg J, Fritsche E, Marx-Stoelting P, Rivière G. De Castelbajac T, et al. Among authors: tal t. Front Toxicol. 2023 Jul 19;5:1216369. doi: 10.3389/ftox.2023.1216369. eCollection 2023. Front Toxicol. 2023. PMID: 37538785 Free PMC article. Review.
New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.
Tal T, Myhre O, Fritsche E, Rüegg J, Craenen K, Aiello-Holden K, Agrillo C, Babin PJ, Escher BI, Dirven H, Hellsten K, Dolva K, Hessel E, Heusinkveld HJ, Hadzhiev Y, Hurem S, Jagiello K, Judzinska B, Klüver N, Knoll-Gellida A, Kühne BA, Leist M, Lislien M, Lyche JL, Müller F, Colbourne JK, Neuhaus W, Pallocca G, Seeger B, Scharkin I, Scholz S, Spjuth O, Torres-Ruiz M, Bartmann K. Tal T, et al. Front Toxicol. 2024 Apr 26;6:1359507. doi: 10.3389/ftox.2024.1359507. eCollection 2024. Front Toxicol. 2024. PMID: 38742231 Free PMC article.
Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods.
Escher BI, Altenburger R, Blüher M, Colbourne JK, Ebinghaus R, Fantke P, Hein M, Köck W, Kümmerer K, Leipold S, Li X, Scheringer M, Scholz S, Schloter M, Schweizer PJ, Tal T, Tetko I, Traidl-Hoffmann C, Wick LY, Fenner K. Escher BI, et al. Among authors: tal t. Arch Toxicol. 2023 May;97(5):1267-1283. doi: 10.1007/s00204-023-03485-5. Epub 2023 Mar 23. Arch Toxicol. 2023. PMID: 36952002 Free PMC article.
The AnimalAssociatedMetagenomeDB reveals a bias towards livestock and developed countries and blind spots in functional-potential studies of animal-associated microbiomes.
Avila Santos AP, Kabiru Nata'ala M, Kasmanas JC, Bartholomäus A, Keller-Costa T, Jurburg SD, Tal T, Camarinha-Silva A, Saraiva JP, Ponce de Leon Ferreira de Carvalho AC, Stadler PF, Sipoli Sanches D, Rocha U. Avila Santos AP, et al. Among authors: tal t. Anim Microbiome. 2023 Oct 5;5(1):48. doi: 10.1186/s42523-023-00267-3. Anim Microbiome. 2023. PMID: 37798675 Free PMC article.
Comparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non-Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular-Course Juvenile Idiopathic Arthritis.
Mannion ML, Amin S, Balevic S, Chang ML, Correll CK, Kearsley-Fleet L, Hyrich KL, Beukelman T; Childhood Arthritis and Rheumatology Research Alliance Registry Investigators and the UK Juvenile Idiopathic Arthritis Biologics Register Investigators. Mannion ML, et al. Arthritis Care Res (Hoboken). 2024 Mar 31. doi: 10.1002/acr.25339. Online ahead of print. Arthritis Care Res (Hoboken). 2024. PMID: 38556945
Resource use and disease severity of children hospitalized for COVID-19 versus multisystem inflammatory syndrome in children (MIS-C) in Canada.
Farrar D, Hepburn CM, Drouin O, El Tal T, Morin MP, Berard R, King M, Thibodeau ML, Baerg K, Beaudoin-Bussières G, Beaufils C, Bennett TL, Benseler S, Chan K, Cyr C, Dahdah N, Donner E, Embree J, Farrell C, Finzi A, Forgie S, Giroux R, Kang K, Lang B, Laxer R, McCrindle B, Orkin J, Papenburg J, Pound C, Price V, Proulx-Gauthier JP, Purewal R, Sadarangani M, Salvadori M, Thibeault R, Top K, Viel-Thériault I, Haddad E, Scuccimarri R, Yeung R, Kakkar F, Morris S. Farrar D, et al. Among authors: el tal t. Can Commun Dis Rep. 2023 Apr 1;49(4):103-112. doi: 10.14745/ccdr.v49i04a03. eCollection 2023 Apr 1. Can Commun Dis Rep. 2023. PMID: 38356877 Free PMC article.
A multi-site pilot randomized clinical trial of the Treatment and Education Approach for Childhood-onset Lupus (TEACH) program: study design and COVID-19 adaptations.
Cunningham NR, Miller A, Ely SL, Reid MR, Danguecan A, Mossad SI, Pereira LF, Abulaban K, Kessler E, Rosenwasser N, Nanda K, Rubinstein T, Reeves M, Kohut SA, Stinson J, Tal TE, Levy DM, Hiraki L, Smitherman EA, Knight AM. Cunningham NR, et al. Among authors: tal te. Pediatr Rheumatol Online J. 2023 Jun 23;21(1):61. doi: 10.1186/s12969-023-00835-6. Pediatr Rheumatol Online J. 2023. PMID: 37353795 Free PMC article. Clinical Trial.
Paediatric inflammatory multisystem syndrome in Canada: population-based surveillance and role of SARS-CoV-2 linkage.
El Tal T, Morin MP, Morris SK, Farrar DS, Berard RA, Kakkar F, Moore Hepburn C, Baerg K, Beaufils C, Bennett TL, Benseler SM, Beaudoin-Bussières G, Chan K, Cyr C, Dahdah N, Donner EJ, Drouin O, Edjoc R, Eljaouhari M, Embree JE, Farrell C, Finzi A, Forgie S, Giroux R, Kang KT, King M, Laffin Thibodeau M, Lang B, Laxer RM, Luu TM, McCrindle BW, Orkin J, Papenburg J, Pound CM, Price VE, Proulx-Gauthier JP, Purewal R, Sadarangani M, Salvadori MI, Thibeault R, Top KA, Viel-Thériault I, Haddad E, Scuccimarri R, Yeung RSM. El Tal T, et al. Pediatr Res. 2023 Nov;94(5):1744-1753. doi: 10.1038/s41390-023-02668-1. Epub 2023 Jun 5. Pediatr Res. 2023. PMID: 37277605 Free PMC article.
Neurological involvement in hospitalized children with SARS-CoV-2 infection: a multinational study.
Yea C, Barton M, Bitnun A, Morris SK, El Tal T, Ulloa-Gutierrez R, Brenes-Chacon H, Yock-Corrales A, Ivankovich-Escoto G, Soriano-Fallas A, Hernandez-de Mezerville M, Gill P, Nateghian A, Aski BH, Manafi AA, Dwilow R, Bullard J, Papenburg J, Scuccimarri R, Lefebvre MA, Cooke S, Dewan T, Restivo L, Lopez A, Sadarangani M, Roberts A, Wong J, Saux NL, Bowes J, Purewal R, Lautermilch J, Foo C, Merckx J, Robinson J, Yeh EA; Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC). Yea C, et al. Among authors: el tal t. Can J Neurol Sci. 2024 Jan;51(1):40-49. doi: 10.1017/cjn.2022.347. Epub 2023 Jan 4. Can J Neurol Sci. 2024. PMID: 36597285 Free PMC article.
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