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P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi.
Tal MC, Hansen PS, Ogasawara HA, Feng Q, Volk RF, Lee B, Casebeer SE, Blacker GS, Shoham M, Galloway SD, Sapiro AL, Hayes B, Dulgeroff LBT, Raveh T, Pothineni VR, Potula HS, Rajadas J, Bastounis EE, Chou S, Robinson WH, Coburn J, Weissman IL, Zaro BW. Tal MC, et al. bioRxiv [Preprint]. 2024 Apr 30:2024.04.29.591704. doi: 10.1101/2024.04.29.591704. bioRxiv. 2024. PMID: 38746193 Free PMC article. Preprint.
SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease.
Strausz S, Abner E, Blacker G, Galloway S, Hansen P, Feng Q, Lee BT, Jones SE, Haapaniemi H, Raak S, Nahass GR, Sanders E; FinnGen; Estonian Genome Centre; Estonian Biobank Research Team; Soodla P, Võsa U, Esko T, Sinnott-Armstrong N, Weissman IL, Daly M, Aivelo T, Tal MC, Ollila HM. Strausz S, et al. Among authors: tal mc. Nat Commun. 2024 Mar 19;15(1):2041. doi: 10.1038/s41467-024-45983-9. Nat Commun. 2024. PMID: 38503741 Free PMC article.
SIRPα controls CD47-dependent platelet clearance in mice and humans.
Shoham M, Yiu YY, Hansen PS, Subramaniam A, Broberg M, Gars E, Raveh T, FinnGen, Weissman IL, Sinnott-Armstrong N, Krishnan A, Ollila HM, Tal MC. Shoham M, et al. Among authors: tal mc. bioRxiv [Preprint]. 2023 Dec 10:2023.12.09.570874. doi: 10.1101/2023.12.09.570874. bioRxiv. 2023. PMID: 38106070 Free PMC article. Preprint.
253 results