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The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.
Sumita K, Lo YH, Takeuchi K, Senda M, Kofuji S, Ikeda Y, Terakawa J, Sasaki M, Yoshino H, Majd N, Zheng Y, Kahoud ER, Yokota T, Emerling BM, Asara JM, Ishida T, Locasale JW, Daikoku T, Anastasiou D, Senda T, Sasaki AT. Sumita K, et al. Among authors: takeuchi k. Mol Cell. 2016 Jan 21;61(2):187-98. doi: 10.1016/j.molcel.2015.12.011. Epub 2016 Jan 7. Mol Cell. 2016. PMID: 26774281 Free PMC article.
Anti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story.
Naffouje R, Grover P, Yu H, Sendilnathan A, Wolfe K, Majd N, Smith EP, Takeuchi K, Senda T, Kofuji S, Sasaki AT. Naffouje R, et al. Among authors: takeuchi k. Cancers (Basel). 2019 Sep 11;11(9):1346. doi: 10.3390/cancers11091346. Cancers (Basel). 2019. PMID: 31514446 Free PMC article. Review.
3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
Konno S, Kobayashi K, Senda M, Funai Y, Seki Y, Tamai I, Schäkel L, Sakata K, Pillaiyar T, Taguchi A, Taniguchi A, Gütschow M, Müller CE, Takeuchi K, Hirohama M, Kawaguchi A, Kojima M, Senda T, Shirasaka Y, Kamitani W, Hayashi Y. Konno S, et al. Among authors: takeuchi k. J Med Chem. 2022 Feb 24;65(4):2926-2939. doi: 10.1021/acs.jmedchem.1c00665. Epub 2021 Jul 27. J Med Chem. 2022. PMID: 34313428
Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ.
Takeuchi K, Senda M, Ikeda Y, Okuwaki K, Fukuzawa K, Nakagawa S, Sasaki M, Sasaki AT, Senda T. Takeuchi K, et al. FEBS J. 2023 Sep;290(18):4419-4428. doi: 10.1111/febs.16763. Epub 2023 Mar 10. FEBS J. 2023. PMID: 36856076 Free PMC article.
4,218 results