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The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetradecanoylphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascades.
Takenobu H, Yamazaki A, Hirata M, Umata T, Mekada E. Takenobu H, et al. J Biol Chem. 2003 May 9;278(19):17255-62. doi: 10.1074/jbc.M211835200. Epub 2003 Feb 28. J Biol Chem. 2003. PMID: 12611888 Free article.
Plk1 regulates liver tumor cell death by phosphorylation of TAp63.
Komatsu S, Takenobu H, Ozaki T, Ando K, Koida N, Suenaga Y, Ichikawa T, Hishiki T, Chiba T, Iwama A, Yoshida H, Ohnuma N, Nakagawara A, Kamijo T. Komatsu S, et al. Among authors: takenobu h. Oncogene. 2009 Oct 15;28(41):3631-41. doi: 10.1038/onc.2009.216. Epub 2009 Aug 10. Oncogene. 2009. PMID: 19668228
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