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The extracellular domain of p185(c-neu) induces density-dependent inhibition of cell growth in malignant mesothelioma cells and reduces growth of mesothelioma in vivo.
Yoneda T, Kumagai T, Nagatomo I, Furukawa M, Yamane H, Hoshino S, Mori M, Takeda Y, Horai T, Nishida S, Watanabe D, Kijima T, Yoshida M, Osaki T, Tachibana I, Greene MI, Kawase I. Yoneda T, et al. Among authors: takeda y. DNA Cell Biol. 2006 Sep;25(9):530-40. doi: 10.1089/dna.2006.25.530. DNA Cell Biol. 2006. PMID: 16989576
Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis.
Furukawa M, Nagatomo I, Kumagai T, Yamadori T, Takahashi R, Yoshimura M, Yoneda T, Takeda Y, Goya S, Matsuoka H, Kijima T, Yoshida M, Osaki T, Tachibana I, Greene MI, Kawase I. Furukawa M, et al. Among authors: takeda y. DNA Cell Biol. 2007 Mar;26(3):178-85. doi: 10.1089/dna.2006.0573. DNA Cell Biol. 2007. PMID: 17417946
Cell surface tetraspanin CD9 mediates chemoresistance in small cell lung cancer.
Kohmo S, Kijima T, Otani Y, Mori M, Minami T, Takahashi R, Nagatomo I, Takeda Y, Kida H, Goya S, Yoshida M, Kumagai T, Tachibana I, Yokota S, Kawase I. Kohmo S, et al. Among authors: takeda y. Cancer Res. 2010 Oct 15;70(20):8025-35. doi: 10.1158/0008-5472.CAN-10-0996. Epub 2010 Oct 12. Cancer Res. 2010. PMID: 20940407
Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy.
Nakanishi K, Takeda Y, Tetsumoto S, Iwasaki T, Tsujino K, Kuhara H, Jin Y, Nagatomo I, Kida H, Goya S, Kijima T, Maeda N, Funahashi T, Shimomura I, Tachibana I, Kawase I. Nakanishi K, et al. Among authors: takeda y. Am J Respir Crit Care Med. 2011 May 1;183(9):1164-75. doi: 10.1164/rccm.201007-1091OC. Epub 2011 Jan 14. Am J Respir Crit Care Med. 2011. PMID: 21239691
Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity: difference in metabolism as a possible mechanism.
Kijima T, Shimizu T, Nonen S, Furukawa M, Otani Y, Minami T, Takahashi R, Hirata H, Nagatomo I, Takeda Y, Kida H, Goya S, Fujio Y, Azuma J, Tachibana I, Kawase I. Kijima T, et al. Among authors: takeda y. J Clin Oncol. 2011 Jul 1;29(19):e588-90. doi: 10.1200/JCO.2010.34.3368. Epub 2011 Apr 18. J Clin Oncol. 2011. PMID: 21502555 No abstract available.
Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer.
Kijima T, Takeuchi K, Tetsumoto S, Shimada K, Takahashi R, Hirata H, Nagatomo I, Hoshino S, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I. Kijima T, et al. Among authors: takeda y. Cancer Sci. 2011 Aug;102(8):1602-4. doi: 10.1111/j.1349-7006.2011.01970.x. Cancer Sci. 2011. PMID: 21767331 Free article.
Early [18F]fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung.
Takahashi R, Hirata H, Tachibana I, Shimosegawa E, Inoue A, Nagatomo I, Takeda Y, Kida H, Goya S, Kijima T, Yoshida M, Kumagai T, Kumanogoh A, Okumura M, Hatazawa J, Kawase I. Takahashi R, et al. Among authors: takeda y. Clin Cancer Res. 2012 Jan 1;18(1):220-8. doi: 10.1158/1078-0432.CCR-11-0868. Epub 2011 Oct 21. Clin Cancer Res. 2012. PMID: 22019513
4,547 results